Description

N,N'-Bis(4-Azidobenzoyl)Cystine is a specialized bifunctional crosslinking agent containing photoreactive azide groups and a cystine-derived disulfide bridge. This compound matters for its unique dual functionality, enabling photoaffinity labeling and the formation of cleavable crosslinks under reducing conditions. It is primarily needed by researchers and manufacturers in the fields of bioconjugation, proteomics, and advanced materials science for applications such as photo-crosslinking studies and the development of stimuli-responsive biomaterials.

Application

• Photoaffinity Labeling in Proteomics: Used to capture and identify transient protein-protein or protein-ligand interactions upon UV light activation.
• Bioconjugation & Immobilization: Serves as a heterobifunctional linker for attaching biomolecules (e.g., peptides, proteins) to surfaces or other molecules, with a cleavable disulfide bond.
• Polymer & Hydrogel Modification: Incorporated into polymer backbones to introduce photo-crosslinkable and redox-responsive properties for smart material design.
• Drug Delivery System Development: Facilitates the creation of carrier systems where the payload release can be triggered by both light and intracellular reducing environments.
• Surface Engineering: Enables the patterned immobilization of bioactive compounds on chips or scaffolds for biosensor and tissue engineering applications.
• Chemical Biology Probes: Acts as a key component in the synthesis of probes for studying cellular processes involving disulfide bond dynamics and light-induced reactions.

Basic Information

Product Name	N,N'-Bis(4-Azidobenzoyl)Cystine
CAS No.	98537-30-5
Molecular Formula	C22H16N8O6S2
Molecular Weight	552.54 g/mol
Synonyms	Bis(4-azidobenzoyl)cystine; Cystine, N,N'-bis(4-azidobenzoyl)-; 4,4'-Diazidodibenzoylcystine; N,N'-Di(4-azidobenzoyl)-L-cystine; L-Cystine, N,N'-bis(4-azidobenzoyl)-; Azidobenzoyl cystine; Photocleavable cystine crosslinker; Bifunctional azide crosslinking agent
EINECS	Contact for details

Quality Control

Our N,N'-Bis(4-Azidobenzoyl)Cystine is produced and handled under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity assessment and spectroscopic methods (NMR, IR) for structural confirmation, to ensure consistency and reliability for research applications. Certificates of Analysis (COA) with detailed batch-specific data are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a freezer at -20°C or below under an inert atmosphere for long-term stability. Due to its light-sensitive and potentially shock-sensitive azide groups, handle with appropriate precautions and avoid exposure to heat, strong acids, and heavy metals.

Specification

Item	Specification
Appearance	Light yellow to yellow powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 1.0%
Solubility	Soluble in DMSO, DMF; sparingly soluble in common organic solvents

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.