Description

Hydroxyethyl-β-Cyclodextrin is a chemically modified cyclodextrin derivative, specifically engineered to enhance the solubility and stability of a wide range of hydrophobic compounds. This product matters for its superior ability to form inclusion complexes, making it an essential solubilizing and stabilizing agent in advanced formulations. It is critically needed by industries such as pharmaceuticals, cosmetics, and agrochemicals for drug delivery, flavor encapsulation, and improving the bioavailability of active ingredients.

Application

• Pharmaceutical Formulations: As a solubility enhancer and stabilizer for poorly water-soluble active pharmaceutical ingredients (APIs) in injectable and oral drug delivery systems.
• Cosmetics & Personal Care: To encapsulate fragrances, vitamins, and other sensitive actives, improving their stability and controlled release in creams, lotions, and serums.
• Food & Flavor Industry: For the encapsulation of flavors, colors, and nutraceuticals, protecting them from degradation and masking undesirable tastes.
• Agrochemicals: To enhance the solubility, stability, and efficacy of pesticides and herbicides, facilitating better formulation and application.
• Chemical Research: As a chiral selector in chromatography and a molecular host in supramolecular chemistry and analytical applications.
• Diagnostic Reagents: Used in the formulation of various diagnostic kits to stabilize sensitive enzymatic or colorimetric components.

Basic Information

Product Name	Hydroxyethyl-β-Cyclodextrin
CAS No.	98513-20-3
Molecular Formula	(C6H10O5)n (C2H4O)m
Molecular Weight	~1135 g/mol (for DS ~0.6, typical)
Synonyms	2-Hydroxyethyl-β-cyclodextrin; HE-β-CD; Hydroxyethyl-β-cyclodextrin; HEB; β-Cyclodextrin, 2-hydroxyethyl ether; (2-Hydroxyethyl)-β-cyclodextrin; Hydroxyethylated β-cyclodextrin; HEBCD
EINECS	Contact for details

Quality Control

Our Hydroxyethyl-β-Cyclodextrin is manufactured under a quality management system. Each batch undergoes rigorous analytical testing to ensure it meets stringent specifications for identity, purity, and performance. Certificates of Analysis (COA) documenting key parameters such as assay, degree of substitution (DS), and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); the container must be kept tightly sealed after opening to prevent absorption of atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms
Assay (HPLC)	≥ 98.0%
Degree of Substitution (DS)	0.4 - 0.7 (Typical: 0.6)
Water Content (KF)	≤ 10.0 %
Residue on Ignition	≤ 0.1 %
Heavy Metals	≤ 10 ppm
Bacterial Endotoxins*	< 0.25 EU/mg
Microbial Limits*	Conforms to USP/EP

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

* Applicable for pharmaceutical grades.