Description

Cremophor (R) A25 is a non-ionic surfactant and solubilizer derived from castor oil, widely recognized for its excellent emulsifying and stabilizing properties. This high-quality excipient is critical for enhancing the solubility and bioavailability of poorly water-soluble active pharmaceutical ingredients (APIs). It is an essential component for formulators in the pharmaceutical, cosmetic, and specialty chemical industries seeking reliable and compliant raw materials for injectable, topical, and oral dosage forms.

Application

• Pharmaceutical solubilizer and emulsifier for parenteral (injectable) formulations.
• Stabilizing agent in topical creams, ointments, and lotions.
• Vehicle for enhancing the oral bioavailability of lipophilic drugs.
• Key excipient in the preparation of self-emulsifying drug delivery systems (SEDDS).
• Emulsifier in cosmetic and personal care products.
• Dispersing agent in agricultural and industrial chemical formulations.
• Component in diagnostic and contrast media preparations.

Basic Information

Product Name	Cremophor (R) A25
CAS No.	68439-49-6
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Polyoxyl 25 Hydrogenated Castor Oil; PEG-25 Hydrogenated Castor Oil; Macrogol 25 Hydrogenated Castor Oil; Kolliphor (R) RH 40 (related grade); Nonionic surfactant from hydrogenated castor oil; Polyoxyethylene (25) hydrogenated castor oil; Oxirane, methyl-, polymer with 1,2,3-propanetriol tri(12-hydroxyoctadecanoate)
EINECS	Contact for details

Quality Control

Our Cremophor A25 is manufactured and tested under a strict quality management system. It is produced to meet the exacting standards required for pharmaceutical and high-grade industrial applications. Certificates of Analysis (COA) documenting key parameters such as hydroxyl value, saponification value, water content, and residue on ignition are available upon request to ensure full traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to yellowish waxy solid
Identification (IR)	Conforms
Hydroxyl Value	Contact for details
Saponification Value	Contact for details
Water Content	≤ 1.0 %
Residue on Ignition	≤ 0.1 %
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.