Description

Hydroxypropyl-β-Cyclodextrin is a chemically modified cyclic oligosaccharide widely used as a versatile solubilizing and stabilizing agent. Its primary value lies in its ability to form non-covalent inclusion complexes with a wide range of hydrophobic molecules, significantly enhancing their aqueous solubility, bioavailability, and stability. This makes it an essential excipient for the pharmaceutical, food, and cosmetic industries, where it is used to improve product performance and delivery.

Application

• Pharmaceutical Solubilization & Delivery: Enhances the solubility and bioavailability of poorly water-soluble active pharmaceutical ingredients (APIs) in oral, injectable, and topical formulations.
• Food & Flavor Encapsulation: Protects sensitive flavors, colors, and nutrients from oxidation, light, and heat, masking unpleasant tastes and controlling release.
• Cosmetic & Personal Care Stabilizer: Improves the stability and skin penetration of active ingredients in creams, lotions, and serums while reducing irritation.
• Chemical & Analytical Chemistry: Used as a chiral selector in chromatography and electrophoresis for enantiomer separation, and as a reaction catalyst or modifier.
• Agrochemical Formulations: Enhances the stability and efficacy of pesticides and herbicides by improving solubility and protecting against degradation.
• Research & Biotechnology: Serves as a tool for protein stabilization, enzyme activity modulation, and cell membrane cholesterol manipulation in biochemical studies.

Basic Information

Product Name	Hydroxypropyl-β-Cyclodextrin
CAS No.	94035-02-6
Molecular Formula	(C6H10O5)7 • (C3H6O)n
Molecular Weight	~1400 g/mol (average, DS-dependent)
Synonyms	HP-β-CD; 2-Hydroxypropyl-β-cyclodextrin; Hydroxypropylbetadex; Heptakis(2-hydroxypropyl)-β-cyclodextrin; β-Cyclodextrin, 2-hydroxypropyl ether; Encapsin HPB; Kleptose HPB; Cavitron 82002
EINECS	Contact for details

Quality Control

Our Hydroxypropyl-β-Cyclodextrin is manufactured under a strict quality management system. We offer grades compliant with major pharmacopeial standards, including USP-NF and EP (Hydroxypropylbetadex), as well as food-grade material meeting FCC guidelines. Every batch undergoes rigorous analytical testing to ensure consistent purity, substitution degree, and performance. A comprehensive Certificate of Analysis (COA) is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive). Keep the container tightly sealed after each use to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White or almost white powder
Identification (IR)	Conforms
Assay (HP-β-CD Content)	≥ 98.0% (on dried basis)
Substitution Degree (Molar, MS)	0.40 - 1.50 (Grade specific)
Water Content	≤ 10.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Microbial Limits	Conforms to USP/EP
pH (10% solution)	5.0 - 7.5
Specific Rotation	+115° to +125°

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.