Description

Dmg-Peg(2000) is a functionalized polyethylene glycol derivative, a bifunctional linker molecule widely used in bioconjugation and pharmaceutical development. Its core value lies in providing a stable, hydrophilic spacer arm that can improve solubility and reduce immunogenicity in therapeutic constructs. This product is essential for researchers and manufacturers in the fields of biopharmaceuticals, diagnostics, and advanced material science who require reliable, high-purity PEGylation reagents.

Application

• Bioconjugation and PEGylation: Used as a linker to attach drugs, proteins, peptides, or antibodies to polyethylene glycol (PEG) chains, enhancing their pharmacokinetic properties.
• Pharmaceutical Development: Serves as a critical intermediate in the synthesis of antibody-drug conjugates (ADCs) and other targeted therapeutic agents.
• Diagnostic Reagent Synthesis: Employed in the preparation of contrast agents, fluorescent probes, and other diagnostic molecules requiring stable, water-soluble linkers.
• Nanoparticle and Liposome Functionalization: Facilitates the surface modification of drug delivery carriers to improve stability, targeting, and circulation time.
• Cross-linking Agent: Acts as a homo-bifunctional cross-linker for coupling amine-containing molecules in biochemical assays and material science.
• Hydrogel and Biomaterial Fabrication: Used as a building block to create biocompatible and tunable hydrogels for tissue engineering and controlled release applications.

Basic Information

Product Name	Dmg-Peg(2000)
CAS No.	1397695-86-1
Molecular Formula	Contact for details
Molecular Weight	~2000 g/mol (Average)
Synonyms	1,2-Dimyristoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-2000] (ammonium salt); DMG-PEG 2000; DMG-PEG2000; 1,2-Dimyristoyl-rac-glycero-3-methoxypolyethylene glycol 2000; Lipid-PEG conjugate; PEGylated DMG lipid; Ionizable lipid-PEG; ALC-0159 (related compound); PEG-DMG
EINECS	Contact for details

Quality Control

Our Dmg-Peg(2000) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency, meeting the high standards required for pharmaceutical research and development. Certificates of Analysis (COA) with detailed specifications for parameters such as assay, functional group content, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under desiccant. This material is hygroscopic (moisture-sensitive). Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture condensation. For long-term storage, keep containers in a dry, inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white waxy solid or paste
Identification (IR)	Conforms to structure
Assay (HPLC)	≥95.0%
Molecular Weight (GPC/SEC)	1900 - 2100 Da
DMG Content	Contact for details
Water Content (KF)	≤1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.