Description

Gelucire 50-13 is a semi-solid, non-ionic surfactant and solubilizer derived from polyethylene glycol (PEG) esters of fatty acids. This versatile excipient is critical for enhancing the bioavailability and dissolution of poorly water-soluble active pharmaceutical ingredients (APIs). It is primarily needed by formulators in the pharmaceutical, nutraceutical, and cosmetic industries for developing solid, semi-solid, and liquid dosage forms.

Application

• Pharmaceutical Formulations: As a key solubilizer and bioavailability enhancer in solid dispersions, capsules, and self-emulsifying drug delivery systems (SEDDS).
• Nutraceutical & Dietary Supplements: Used to improve the absorption of fat-soluble vitamins and other lipophilic bioactive compounds in softgel and tablet formulations.
• Cosmetic & Personal Care: Functions as an emulsifier, stabilizer, and texture enhancer in creams, ointments, and topical preparations.
• Hot Melt Coating & Granulation: Serves as a matrix former and binder in melt granulation and coating processes for controlled-release applications.
• Food Industry: Acts as an emulsifier and stabilizer in certain food-grade applications, subject to compliance with relevant regulations.

Basic Information

Product Name	Gelucire 50-13
CAS No.	121548-05-8
Molecular Formula	Mixture (Polyethylene glycol esters of fatty acids)
Molecular Weight	N/A (Mixture)
Synonyms	Lauroyl Polyoxyl-32 Glycerides; PEG-32 Glyceryl Laurate; Glycerol and PEG-32 Esters of Lauric Acid; Polyoxylglycerides (Type: Lauroyl Polyoxyl-32 Glycerides); Gattefossé Gelucire 50/13; 50/13 Gelucire
EINECS	Contact for details

Quality Control

Our Gelucire 50-13 is manufactured and tested under a strict quality management system. We ensure compliance with relevant pharmaceutical excipient standards, including potential ICH guidelines for impurities. A comprehensive Certificate of Analysis (COA) is provided with each batch, detailing key parameters such as acid value, saponification value, hydroxyl value, and melting behavior.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (typically 15-25°C). Avoid exposure to excessive heat and moisture to maintain product integrity.

Specification

Item	Specification
Description	White to off-white waxy solid
Identification (IR)	Conforms
Melting Point / Drop Point	Approx. 50°C
Acid Value	≤ 2.0 mg KOH/g
Saponification Value	65 - 85 mg KOH/g
Hydroxyl Value	40 - 60 mg KOH/g
Water Content	≤ 1.0 %

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.