Description

3-Methylenecyclobutanecarbonyl Chloride is a highly reactive and versatile acid chloride derivative of 3-methylenecyclobutanecarboxylic acid. This compound serves as a critical building block in advanced organic synthesis, enabling the efficient introduction of the 3-methylenecyclobutylcarbonyl moiety into target molecules. It is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and complex intermediates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and metabolic diseases.
• Agrochemical Synthesis: Used in the development of next-generation herbicides and fungicides with unique modes of action.
• Polymer Chemistry: Acts as a monomer or cross-linking agent for creating specialty polymers with tailored thermal and mechanical properties.
• Material Science Research: Employed in the development of advanced organic materials, including liquid crystals and organic semiconductors.
• Peptide Mimetics: Facilitates the incorporation of constrained, non-natural amino acid structures into peptide chains to enhance stability and bioavailability.
• Chemical Biology Probes: Useful for labeling biomolecules or creating activity-based probes for enzyme studies.

Basic Information

Product Name	3-Methylenecyclobutanecarbonyl Chloride
CAS No.	98198-78-8
Molecular Formula	C6H7ClO
Molecular Weight	130.57 g/mol
Synonyms	3-Methylenecyclobutanecarboxylic acid chloride; 3-Methylenecyclobutanecarboxyl chloride; 3-Methylenebutane-1-carbonyl chloride; Cyclobutane-1-carbonyl chloride, 3-methylene-; 3-Methylene-1-cyclobutanecarbonyl chloride
EINECS	Contact for details

Quality Control

Our 3-Methylenecyclobutanecarbonyl Chloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including NMR, IR, and GC/HPLC analysis, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We adhere to cGMP principles for pharmaceutical-grade intermediates, ensuring traceability and documentation for regulatory submissions.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at 2-8°C under an inert atmosphere (e.g., nitrogen or argon). Due to its hygroscopic and moisture-sensitive nature, containers must be kept sealed and handled under dry conditions to prevent hydrolysis. Keep away from strong bases, oxidizing agents, and alcohols.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.