Description

4-Methoxy-3-(trifluoromethyl)benzoyl chloride is a versatile and highly reactive aromatic acid chloride derivative. This compound serves as a critical building block in advanced organic synthesis, enabling the efficient introduction of the 4-methoxy-3-(trifluoromethyl)benzoyl moiety. It is essential for research and development chemists and process engineers in the pharmaceutical and agrochemical industries, where it is used to create novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring the trifluoromethyl and methoxy substituted benzoyl group for enhanced bioactivity and metabolic stability.
• Agrochemical Synthesis: Used in the manufacturing of advanced herbicides, fungicides, and insecticides, where the trifluoromethyl group often contributes to improved efficacy and environmental profile.
• Liquid Crystal Materials: Acts as a building block for the production of specialty chemicals used in liquid crystal displays (LCDs) and other electronic materials.
• Polymer Chemistry: Employed as a monomer or modifying agent in the synthesis of high-performance polymers, coatings, and resins with specific thermal or chemical resistance properties.
• Organic Synthesis Reagent: A valuable reagent for peptide coupling, esterification, and amidation reactions in research laboratories and pilot-scale production.
• Dye and Pigment Manufacturing: Intermediate in the synthesis of complex dyes and organic pigments, contributing to color fastness and specific spectral properties.

Basic Information

Product Name	4-Methoxy-3-(Trifluoromethyl)Benzoyl Chloride
CAS No.	98187-18-9
Molecular Formula	C9H6ClF3O2
Molecular Weight	238.59 g/mol
Synonyms	3-(Trifluoromethyl)-4-methoxybenzoyl chloride; 4-Methoxy-3-(trifluoromethyl)benzoic acid chloride; 4-Methoxy-alpha,alpha,α-trifluoro-m-toluoyl chloride; p-Methoxy-m-(trifluoromethyl)benzoyl chloride; 98187-18-9; 4-Methoxy-3-trifluoromethylbenzoyl chloride
EINECS	Contact for details

Quality Control

Our 4-Methoxy-3-(trifluoromethyl)benzoyl chloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic and moisture-sensitive nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent hydrolysis. Keep away from strong bases, oxidizing agents, and sources of ignition.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.