Description

Renin Inhibitory Peptide, 4-Amino-5-Cyclohexyl-3-Hydroxypentanoic Acid is a synthetic peptide derivative designed to specifically inhibit the renin enzyme, a key component of the renin-angiotensin system (RAS). This targeted action makes it a valuable research tool for studying hypertension, cardiovascular diseases, and renal function. It is primarily utilized by pharmaceutical researchers, academic institutions, and biotechnology companies engaged in drug discovery and biochemical pathway analysis.

Application

• Biomedical Research: A critical tool for in vitro and in vivo studies of the renin-angiotensin-aldosterone system (RAAS) and its role in blood pressure regulation.
• Drug Discovery & Development: Serves as a reference standard, lead compound, or pharmacophore model for developing novel antihypertensive and cardiovascular therapeutics.
• Enzyme Inhibition Studies: Used to investigate renin enzyme kinetics, mechanism of action, and structure-activity relationships (SAR) in biochemical assays.
• Academic Research: Employed in university and institutional labs for fundamental research into hypertension, heart failure, and kidney disease pathophysiology.
• Pharmaceutical Intermediate: Can act as a key synthetic building block or precursor for more complex peptide-based active pharmaceutical ingredients (APIs).
• Diagnostic Development: Potential use in the development of diagnostic assays to measure renin activity or screen for renin inhibitors.

Basic Information

Product Name	Renin Inhibitory Peptide, 4-Amino-5-Cyclohexyl-3-Hydroxypentanoic Acid
CAS No.	98105-34-1
Molecular Formula	C11H21NO3
Molecular Weight	215.29 g/mol
Synonyms	4-Amino-5-cyclohexyl-3-hydroxypentanoic acid; (3R,4S)-4-Amino-5-cyclohexyl-3-hydroxypentanoic acid; Renin Inhibitor Peptide Fragment; ACHPA; H-ACHPA-OH; (3R,4S)-ACHPA; Pentanoic acid, 4-amino-5-cyclohexyl-3-hydroxy-; A building block for renin inhibitors
EINECS	Contact for details

Quality Control

Our Renin Inhibitory Peptide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, chiral analysis for stereochemical integrity, and comprehensive identification tests. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with research-grade specifications. Our quality commitment supports reproducible and reliable results for your critical research applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Chiral Purity	≥ 99.0% (3R,4S)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.