Description

Todralazine is a pharmaceutical intermediate and active pharmaceutical ingredient (API) belonging to the chemical class of hydrazinophthalazine derivatives. This compound is of significant commercial interest for its role in the synthesis of specialized cardiovascular and other therapeutic agents. It is primarily utilized by pharmaceutical manufacturers, research institutions, and fine chemical suppliers engaged in advanced drug development and production.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of antihypertensive and vasodilator APIs.
• Active Pharmaceutical Ingredient (API): Used in the formulation of finished dosage forms for cardiovascular treatments.
• Research & Development: Serves as a critical reference standard and starting material in medicinal chemistry for exploring new pharmacologically active molecules.
• Fine Chemical Synthesis: Employed in multi-step organic synthesis for creating complex, high-value specialty chemicals.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for cGMP production.
• Analytical Standard: Used in quality control laboratories for method development, validation, and impurity profiling via HPLC and other techniques.

Basic Information

Product Name	Todralazine
CAS No.	14679-73-3
Molecular Formula	C13H14N4
Molecular Weight	226.28 g/mol
Synonyms	1-Hydrazino-4-methylphthalazine; 1-Hydrazinophthalazine, 4-methyl-; 4-Methyl-1-hydrazinophthalazine; 4-Methylphthalazine-1-hydrazine; BTS 13622; SQ 11436; Todralazinum; Todralazina
EINECS	Contact for details

Quality Control

Our Todralazine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Quality assurance protocols are designed to meet the stringent requirements of pharmaceutical ingredient supply. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your regulatory and production needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which may affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.