Description

Valsartan CAS NO 13862-53-4 is a high-purity, non-peptide angiotensin II receptor antagonist (ARB) used as a key active pharmaceutical ingredient (API). It is critical for the formulation of antihypertensive and heart failure medications, offering targeted therapeutic action. This compound is essential for pharmaceutical manufacturers and research institutions developing cardiovascular therapies, requiring consistent quality and reliable supply.

Application

• Pharmaceutical API: Primary active ingredient in tablets and capsules for the treatment of hypertension (high blood pressure).
• Cardiovascular Drug Formulations: Used in combination therapies for heart failure and post-myocardial infarction management.
• Research & Development: Reference standard and building block in pharmacological studies and new drug discovery programs.
• Generic Drug Manufacturing: Sourcing for the production of bioequivalent generic versions of branded ARB medications.
• Clinical Trial Materials: Supply of GMP-grade material for Phase I-IV clinical studies.
• Veterinary Pharmaceuticals: Potential application in developing cardiovascular treatments for animals.

Basic Information

Product Name	Valsartan
CAS No.	13862-53-4
Molecular Formula	C24H29N5O3
Molecular Weight	435.52 g/mol
Synonyms	N-Valeryl-N-[[2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-L-valine; Diovan (Brand Name); (S)-N-(1-Oxopentyl)-N-[[2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-L-valine; CGP 48933; L-Valine, N-(1-oxopentyl)-N-[[2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-, (S)-; Valsartan USP; Valsartan EP
EINECS	Contact for details

Quality Control

Our Valsartan is manufactured under strict quality systems to meet or exceed USP, EP, and ICH Q7 guidelines for active pharmaceutical ingredients. Every batch undergoes comprehensive analytical testing including HPLC for assay and related substances, residual solvent analysis, and microbiological examination. A Certificate of Analysis (COA) documenting full compliance with specifications is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept in a dry environment to prevent degradation. Keep the container tightly sealed when not in use.

Specification

Item	Specification
Appearance	White or almost white powder
Identification (IR)	Conforms to reference standard
Identification (HPLC)	Retention time corresponds to reference
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Related Substances (HPLC)	Individual impurity: NMT 0.15% Total impurities: NMT 0.5%
Water (KF Titration)	NMT 2.0%
Residue on Ignition	NMT 0.1%
Heavy Metals	NMT 20 ppm
Microbial Enumeration	Complies with EP/USP limits

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.