Description

Guanosine Diphosphate n-Chloroacetylhydrazone is a chemically modified nucleotide derivative designed for advanced biochemical research and synthesis. This compound is critical for researchers and developers working on nucleotide-based probes, enzyme inhibitors, and targeted drug delivery systems. It serves as a key building block in pharmaceutical R&D, particularly in the development of antiviral agents and metabolic pathway modulators. Its specific structure makes it valuable for creating conjugates with enhanced biological activity and specificity.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the synthesis of novel antiviral and anticancer nucleotide analogs.
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies, particularly those involving GTP-binding proteins and kinases.
• Probe Development: Acts as a starting material for synthesizing fluorescent or affinity-labeled nucleotide probes for cellular imaging and detection.
• Conjugate Synthesis: The reactive hydrazone moiety enables conjugation with various targeting ligands, antibodies, or nanoparticles for targeted therapeutic applications.
• Metabolic Pathway Analysis: Utilized in tracing and modulating specific nucleotide-dependent metabolic processes within cells.
• Enzyme Mechanism Studies: Helps in elucidating the binding and catalytic mechanisms of enzymes that interact with guanosine derivatives.

Basic Information

Product Name	Guanosine Diphosphate n-Chloroacetylhydrazone
CAS No.	98063-02-6
Molecular Formula	C12H15ClN6O10P2
Molecular Weight	500.71 g/mol
Synonyms	GDP-Chloroacetylhydrazone; Guanosine-5'-diphosphate chloroacetylhydrazone; 5'-GDP N-chloroacetylhydrazone; Chloroacetylguanosine diphosphate hydrazone; Guanosine diphosphate chloroacetyl hydrazone; GDP-CAH; 1-[2-(Guanosine-5'-diphospho)hydrazinyl]-2-chloroethanone
EINECS	Contact for details

Quality Control

Our Guanosine Diphosphate n-Chloroacetylhydrazone is produced under stringent quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and tests for residual solvents and moisture content. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research or development specifications. Our quality commitment supports applications requiring high-purity biochemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This compound is hygroscopic (moisture-sensitive) and light-sensitive (store away from light). For long-term storage, consider desiccant and under an inert atmosphere to maintain stability. Allow the sealed container to equilibrate to room temperature before opening to prevent moisture condensation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Solvent Residues (GC)	Meets ICH guidelines
Biological Activity	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.