Description

4-Bromo-2-Chlorophenyl Isothiocyanate is a versatile and highly reactive organosulfur compound, serving as a critical building block in advanced organic synthesis. Its value lies in the unique reactivity of the isothiocyanate group, which readily undergoes addition and cyclization reactions to form heterocyclic scaffolds. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, where it is used to develop novel active ingredients and complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of potential drug candidates, particularly for creating benzothiazole and thiourea derivatives with biological activity.
• Agrochemical Research: Building block for developing new herbicides, fungicides, and insecticides, leveraging the bioactivity of the phenyl isothiocyanate core.
• Chemical Synthesis Reagent: Used in organic laboratories for the preparation of thioureas, thiosemicarbazides, and other sulfur-containing heterocycles via nucleophilic addition reactions.
• Material Science: Intermediate in the development of specialty polymers and functional materials that incorporate sulfur and nitrogen motifs.
• Ligand Synthesis: Starting material for creating novel chelating agents and ligands used in coordination chemistry and catalysis.

Basic Information

Product Name	4-Bromo-2-Chlorophenyl Isothiocyanate
CAS No.	98041-69-1
Molecular Formula	C7H3BrClNS
Molecular Weight	248.53 g/mol
Synonyms	2-Chloro-4-bromophenyl isothiocyanate; 1-Bromo-3-chloro-4-isothiocyanatobenzene; 4-Bromo-2-chlorobenzene isothiocyanate; Isothiocyanic acid, 4-bromo-2-chlorophenyl ester; 4-Bromo-2-chloro-1-isothiocyanatobenzene; (4-Bromo-2-chlorophenyl)isothiocyanate
EINECS	Contact for details

Quality Control

Our 4-Bromo-2-Chlorophenyl Isothiocyanate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via FT-IR and NMR spectroscopy, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, open flames, and strong bases. Due to its light-sensitive nature, prolonged exposure to light should be avoided.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.