Description

2-Bromoethyl Isothiocyanate is a versatile bifunctional organic building block containing both a reactive bromoalkyl group and an isothiocyanate moiety. This compound is valued for its ability to act as a key synthetic intermediate in the preparation of more complex heterocyclic and functionalized molecules. It is primarily sought by research and development chemists in the pharmaceutical, agrochemical, and specialty chemical industries for applications in medicinal chemistry and material science.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the synthesis of novel drug candidates, particularly those with potential anticancer or antimicrobial activity.
• Agrochemical Synthesis: Used in the research and development of new pesticides and herbicides, leveraging its reactive functional groups.
• Chemical Biology Probe Development: The isothiocyanate group can react with amines, making it useful for labeling proteins or other biomolecules in research settings.
• Heterocyclic Chemistry: A key starting material for the construction of various sulfur- and nitrogen-containing heterocycles, such as thiazoles and thiazolidines.
• Polymer Modification: Can be used to introduce functional side chains or cross-linking points into polymer backbones.
• Ligand Synthesis for Catalysis: Employed in the preparation of specialized ligands for metal-catalyzed reactions.

Basic Information

Product Name	2-Bromoethyl Isothiocyanate
CAS No.	1483-41-6
Molecular Formula	C3H4BrNS
Molecular Weight	166.04 g/mol
Synonyms	2-Bromoethyl isothiocyanate; (2-Bromoethyl)isothiocyanate; 1-Bromo-2-isothiocyanatoethane; Isothiocyanic acid, 2-bromoethyl ester; NSC 401122; 2-Bromoethyl mustard oil; β-Bromoethyl isothiocyanate
EINECS	216-053-1

Quality Control

Our 2-Bromoethyl Isothiocyanate is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including chromatographic purity analysis and identity confirmation, to ensure it meets the high standards required for research and industrial synthesis. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting key parameters such as assay and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong bases and incompatible materials. Due to its lachrymatory and potentially hazardous nature, appropriate personal protective equipment should be used when handling.

Specification

Item	Specification
Appearance	Clear, colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.