Description

Ethoxycarbonyl Isothiocyanate is a versatile and highly reactive organic building block used in advanced chemical synthesis. Its primary value lies in its ability to introduce both the ethoxycarbonyl and isothiocyanate functional groups in a single step, facilitating the efficient construction of complex heterocyclic and thiourea derivatives. This compound is essential for research and development chemists in the pharmaceutical, agrochemical, and specialty chemical industries, where it serves as a key intermediate for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A critical reagent for synthesizing thiourea derivatives and heterocyclic compounds with potential biological activity.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides by incorporating the thiocarbamate moiety.
• Peptide Chemistry & Bioconjugation: Acts as a coupling agent for modifying peptides, proteins, and other biomolecules.
• Polymer & Material Science: Employed in the synthesis of functional polymers, coatings, and resins with specific thiocarbonyl properties.
• Chemical Research & Development: Serves as a fundamental building block in organic synthesis for creating libraries of novel chemical entities.
• Dye & Pigment Manufacturing: Used in the synthesis of sulfur-containing dyes and specialty colorants.

Basic Information

Product Name	Ethoxycarbonyl Isothiocyanate
CAS No.	16182-04-0
Molecular Formula	C4H5NO2S
Molecular Weight	131.15 g/mol
Synonyms	Ethyl Isothiocyanatoformate; Ethoxycarbonyl Mustard Oil; Carbethoxy Isothiocyanate; Isothiocyanatoformic Acid Ethyl Ester; Ethyl Carbonisothiocyanatidate; Ethyl Ester of Isothiocyanatoformic Acid; NSC 401119; Ethyl Isothiocyanatoformate
EINECS	Contact for details

Quality Control

Our Ethoxycarbonyl Isothiocyanate is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. We provide comprehensive analytical data, including purity assay and impurity profiling via modern chromatographic techniques. A Certificate of Analysis (COA) detailing specifications and test results is available for every batch upon request, supporting your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated place at a controlled room temperature (15-25°C). Due to its highly volatile nature, ensure containers are securely sealed and stored upright. Keep away from heat, sparks, and open flame. Store separately from strong bases, oxidizing agents, and moisture.

Specification

Item	Specification
Appearance	Clear, colorless to pale yellow liquid
Identification (IR)	Conforms
Assay (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Refractive Index (n20D)	1.480 - 1.490
Density (g/mL at 20°C)	1.10 - 1.20

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.