Description

2-Iodophenyl Isothiocyanate is a versatile organosulfur and organoiodine building block of significant interest in synthetic organic chemistry. Its value lies in its bifunctional reactivity, where the isothiocyanate group serves as an electrophile for nucleophilic addition and the iodine atom enables powerful cross-coupling transformations. This compound is primarily sought after by researchers and process chemists in the pharmaceutical and agrochemical industries for the development of novel heterocyclic compounds and active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of benzothiazole, thiourea, and thiazolidinone derivatives with potential biological activity.
• Agrochemical Research: Used in creating novel pesticidal and herbicidal agents by incorporating the iodine and thiocyanate functionalities into lead structures.
• Ligand Synthesis: Serves as a starting material for preparing specialized ligands used in catalysis and metal-organic frameworks (MOFs).
• Chemical Biology Probe Development: Utilized to create isothiocyanate-based affinity probes for protein labeling and activity-based protein profiling (ABPP).
• Material Science: Acts as a monomer or cross-linking agent in the synthesis of functional polymers and advanced materials.

Basic Information

Product Name	2-Iodophenyl Isothiocyanate
CAS No.	98041-44-2
Molecular Formula	C7H4INS
Molecular Weight	261.08 g/mol
Synonyms	1-Iodo-2-isothiocyanatobenzene; o-Iodophenyl Isothiocyanate; 2-Isothiocyanato-1-iodobenzene; (2-Iodophenyl)isothiocyanate; NSC 405124; 2-Iodophenyl mustard oil; 2-Iodo-benzenisothiocyanate
EINECS	Contact for details

Quality Control

Our 2-Iodophenyl Isothiocyanate is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and development. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee reproducible results and supply chain integrity.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	Off-white to pale yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.