Description

5-(Azidomethyl)-2,4(1H,3H)-Pyrimidinedione is a specialized heterocyclic organic compound featuring an azidomethyl functional group, making it a valuable building block for chemical synthesis. This compound is critical for researchers and manufacturers developing novel pharmaceuticals and advanced materials through click chemistry and other bioorthogonal reactions. It is primarily utilized by the pharmaceutical, agrochemical, and life science research industries for the synthesis of nucleoside analogs, prodrugs, and targeted molecular probes.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel antiviral and anticancer nucleoside analogs.
• Click Chemistry Reagent: Utilized in Huisgen 1,3-dipolar cycloaddition reactions for bioconjugation and polymer modification due to its reactive azide group.
• Prodrug Synthesis: Serves as a precursor for designing prodrugs with targeted release mechanisms.
• Bioconjugation & Labeling: Used to attach fluorescent dyes, affinity tags, or other functional moieties to biomolecules for diagnostic and research applications.
• Agrochemical Research: Employed in the synthesis of new active ingredients with potential herbicidal or pesticidal activity.
• Material Science: Acts as a cross-linking agent or functional monomer in the creation of advanced polymeric materials.

Basic Information

Product Name	5-(Azidomethyl)-2,4(1H,3H)-Pyrimidinedione
CAS No.	98024-77-2
Molecular Formula	C5H5N5O2
Molecular Weight	167.13 g/mol
Synonyms	5-(Azidomethyl)uracil; 5-Azidomethyluracil; 5-(Azidomethyl)-2,4-dihydroxypyrimidine; 5-(Azidomethyl)-1H-pyrimidine-2,4-dione; 5-(Azidomethyl)pyrimidine-2,4(1H,3H)-dione; 5-(N3-Methyl)uracil; Uracil, 5-(azidomethyl)-
EINECS	Contact for details

Quality Control

Our 5-(Azidomethyl)-2,4(1H,3H)-Pyrimidinedione is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets the high standards required for research and synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C) under an inert atmosphere (e.g., nitrogen or argon) to prevent oxidation. Keep away from heat, sparks, open flames, and incompatible materials. This material is moisture-sensitive; ensure the container is sealed after each use.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.