Description

3-Pyridinecarbonyl Chloride, 1,2-Dihydro-2-Thioxo- is a specialized heterocyclic building block of significant interest in advanced organic synthesis. This compound matters for its role as a key precursor in the development of novel pharmacologically active molecules and functional materials. It is primarily needed by research and development chemists in the pharmaceutical, agrochemical, and material science industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Serves as a critical synthon in the synthesis of potential drug candidates, particularly those targeting neurological and oncological pathways.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides with novel modes of action.
• Ligand Synthesis: Acts as a precursor for creating complex ligands used in catalysis and metal-organic frameworks (MOFs).
• Material Science: Employed in the synthesis of functionalized polymers and advanced organic electronic materials.
• Chemical Biology Probes: Utilized to develop activity-based probes and other tools for studying enzymatic processes and protein interactions.
• Academic & Contract Research: A valuable reagent for methodological development and exploratory chemistry in university and CRO laboratories.

Basic Information

Product Name	3-Pyridinecarbonyl Chloride, 1,2-Dihydro-2-Thioxo-
CAS No.	97936-36-2
Molecular Formula	C6H4ClNOS
Molecular Weight	173.62 g/mol
Synonyms	2-Mercaptonicotinoyl Chloride; 2-Thioxo-1,2-dihydropyridine-3-carbonyl Chloride; 2-Mercaptonicotinic Acid Chloride; 3-Carbamoyl-2-mercaptopyridine Hydrochloride (related); 2-Sulfanylpyridine-3-carbonyl Chloride; 1,2-Dihydro-2-thioxo-3-pyridinecarbonyl Chloride; 2-Thioxo-1,2-dihydro-3-pyridinecarbonyl chloride
EINECS	Contact for details

Quality Control

Our 3-Pyridinecarbonyl Chloride, 1,2-Dihydro-2-Thioxo- is produced under strict quality management systems. Each batch undergoes comprehensive analytical characterization including HPLC, NMR, and IR spectroscopy to ensure identity, purity, and consistency. Certificates of Analysis (COA) documenting all critical quality attributes are available upon request, supporting your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	Off-white to pale yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.