Description

Carbocyclic Inosine Monophosphate is a synthetic nucleoside monophosphate analog where the ribose sugar moiety is replaced by a carbocyclic ring system. This structural modification enhances its metabolic stability, making it a valuable intermediate and research tool in medicinal chemistry and biochemistry. It is primarily utilized by pharmaceutical R&D teams and fine chemical manufacturers for developing novel antiviral and anticancer therapeutics, as well as in biochemical studies investigating nucleotide metabolism and enzyme function.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel carbocyclic nucleoside analogs with potential antiviral (e.g., against herpesviruses, hepatitis) and anticancer activity.
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies to investigate the mechanisms of nucleotide-metabolizing enzymes like kinases and phosphorylases.
• Pro-drug Development: Serves as a precursor for the development of membrane-permeable pro-drugs designed to improve cellular uptake and therapeutic efficacy.
• Molecular Biology: Potential utility in the study of RNA structure and function, or as a non-hydrolyzable analog in mechanistic studies.
• Reference Standard: Employed as a high-purity analytical standard in quality control laboratories for method development and validation in pharmaceutical analysis.

Basic Information

Product Name	Carbocyclic Inosine Monophosphate
CAS No.	97727-48-5
Molecular Formula	C11H15N4O7P
Molecular Weight	346.23 g/mol
Synonyms	cIMP; Carbocyclic IMP; (1S,4R)-4-Hydroxy-2-cyclopenten-1-yl)methyl 6-oxo-6,9-dihydro-1H-purin-9-yl dihydrogen phosphate; 9-[(1S,4R)-4-Hydroxy-2-cyclopenten-1-yl]methyl]-6-oxo-1H-purin-9-ium dihydrogen phosphate; Carbocyclic inosine 5'-monophosphate; Carbocyclic Inosinic Acid
EINECS	Contact for details

Quality Control

Our Carbocyclic Inosine Monophosphate is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and tests for residual solvents and moisture content. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research or production specifications. Custom purity grades and analytical packages are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.