Description

2',5-Dichloro-2'-Deoxycytidine is a halogenated nucleoside derivative of significant interest in advanced pharmaceutical research and development. This compound serves as a critical synthetic intermediate and a versatile building block for the creation of novel therapeutic agents, particularly in the fields of antiviral and anticancer drug discovery. It is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and fine chemical synthesis sectors who require high-purity, specialized nucleoside analogs for their development pipelines.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel nucleoside-based antiviral and anticancer prodrugs.
• Antiviral Research: Used in the development of potential therapeutic agents targeting DNA viruses.
• Biochemical Tool: Employed in enzymatic studies and as a substrate analog to investigate nucleoside metabolism and related pathways.
• Medicinal Chemistry: Serves as a versatile scaffold for structure-activity relationship (SAR) studies to optimize drug potency and selectivity.
• Oligonucleotide Synthesis: Can be incorporated into modified oligonucleotides for antisense or diagnostic applications.
• Academic & Contract Research: Utilized in university and CRO laboratories for fundamental research in chemical biology and drug discovery.

Basic Information

Product Name	2',5-Dichloro-2'-Deoxycytidine
CAS No.	97716-27-3
Molecular Formula	C9H11Cl2N3O4
Molecular Weight	296.11 g/mol
Synonyms	2',5-Dichloro-2'-deoxycytidine; 5-Chloro-2'-deoxy-2'-chlorocytidine; 2'-Deoxy-2',5-dichlorocytidine; 1-((2R,4S,5R)-4-Hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-chloro-2-(chloroamino)pyrimidin-4(1H)-one; 2'-Deoxy-2',5-dichloro-cytidine; 2',5-DiCl-2'-dCyd
EINECS	Contact for details

Quality Control

Our 2',5-Dichloro-2'-Deoxycytidine is produced under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and development applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We adhere to relevant industry standards and can support development projects requiring material for pre-clinical studies.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/IR)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single unknown impurity ≤ 0.5%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.