Description

1,3-Dioxolane-4-Carbonyl Chloride, 2,2-Dimethyl-, (4R)- (9Ci) is a high-purity, chiral acyl chloride derivative that serves as a critical building block in advanced organic synthesis. Its value lies in its ability to introduce a protected glyceraldehyde-like chiral fragment, enabling the stereoselective construction of complex molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and fine chemical industries, particularly for developing active pharmaceutical ingredients (APIs) and novel chiral intermediates.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of nucleoside analogs, antiviral drugs, and other bioactive molecules.
• Asymmetric Synthesis: Used in the preparation of enantiomerically pure compounds for medicinal chemistry and catalysis research.
• Fine Chemical Production: Serves as a precursor in the manufacture of specialty chemicals, flavors, and fragrances requiring specific stereochemistry.
• Academic & R&D: A valuable reagent for exploring new synthetic methodologies and constructing complex natural product frameworks in laboratory settings.
• Material Science: Potential monomer or cross-linking agent for creating polymers with specific functional or chiral properties.

Basic Information

Product Name	1,3-Dioxolane-4-Carbonyl Chloride, 2,2-Dimethyl-, (4R)- (9Ci)
CAS No.	97673-82-0
Molecular Formula	C6H9ClO3
Molecular Weight	164.59 g/mol
Synonyms	(4R)-2,2-Dimethyl-1,3-dioxolane-4-carbonyl chloride; (R)-2,2-Dimethyl-1,3-dioxolane-4-carbonyl chloride; (R)-(-)-2,2-Dimethyl-1,3-dioxolane-4-carbonyl chloride; D-Glyceraldehyde Acetonide Carbonyl Chloride; (R)-Glyceraldehyde Acetonide Carbonyl Chloride; (4R)-2,2-Dimethyl-1,3-dioxolan-4-carbonyl chloride
EINECS	Contact for details

Quality Control

Our production of 1,3-Dioxolane-4-Carbonyl Chloride, 2,2-Dimethyl-, (4R)- adheres to stringent quality protocols to ensure batch-to-batch consistency and high chiral purity. Each lot is characterized using advanced analytical techniques including chiral HPLC, NMR, and IR spectroscopy. A comprehensive Certificate of Analysis (COA) detailing purity, enantiomeric excess, and impurity profile is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Due to its hygroscopic and moisture-sensitive nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition. Keep away from heat, sparks, open flames, and incompatible materials such as strong bases, alcohols, and amines.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Enantiomeric Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.