Description

4-(Bromoacetamido)Benzylcarazolol is a specialized synthetic intermediate featuring a reactive bromoacetamido group. This compound is of significant value in pharmaceutical research and development, particularly for the synthesis and modification of β-adrenergic receptor ligands. It is primarily sought after by research institutions and pharmaceutical companies engaged in the development of novel cardiovascular and neurological therapeutics, as well as for creating affinity labels for receptor studies.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of advanced β-blocker analogs and other carazolol-derived active pharmaceutical ingredients (APIs).
• Biochemical Research: Used as an affinity labeling reagent for the study and isolation of β-adrenergic receptors due to its reactive bromoacetyl moiety.
• Proteomics & Molecular Biology: Employed in the development of chemical probes for target identification and protein interaction studies within signal transduction pathways.
• Medicinal Chemistry: Serves as a versatile precursor for structure-activity relationship (SAR) studies aimed at optimizing drug potency and selectivity.
• High-Throughput Screening: Can be utilized to create compound libraries for screening against cardiovascular and CNS-related targets.

Basic Information

Product Name	4-(Bromoacetamido)Benzylcarazolol
CAS No.	97458-54-3
Molecular Formula	C24H28BrN3O3
Molecular Weight	486.41 g/mol
Synonyms	4-(Bromoacetamido)benzyl carazolol; 1-(9H-Carbazol-4-yloxy)-3-[(2-{[4-(2-bromoacetamido)benzyl]amino}ethyl)amino]-2-propanol; Carazolol, 4-(bromoacetamido)benzyl-; BRL 44408 maleate (related compound); β-adrenergic receptor affinity label
EINECS	Contact for details

Quality Control

Our 4-(Bromoacetamido)Benzylcarazolol is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and residual solvent analysis. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to ensure traceability and compliance with your research or development protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C for long-term stability. The compound is light-sensitive; handling should be performed under appropriate conditions to minimize degradation. Keep container tightly sealed in a dry environment to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.