Description

1,2-Cyclobutanedicarbonyl Dichloride, 1,2-Dimethyl-, trans- (9Ci) is a high-purity, trans-configured cyclic diacid chloride derivative, serving as a critical chiral building block in advanced organic synthesis. Its rigid cyclobutane core and reactive acyl chloride groups make it an invaluable precursor for constructing complex molecular architectures with precise stereochemistry. This compound is essential for research and development in the pharmaceutical and agrochemical industries, particularly for synthesizing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of complex drug candidates, including protease inhibitors and other biologically active molecules.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides with specific stereochemical requirements.
• Polymer Chemistry: Serves as a monomer or cross-linking agent for producing specialty polymers with unique thermal and mechanical properties.
• Ligand and Catalyst Development: Employed in the preparation of chiral ligands and organocatalysts for asymmetric synthesis.
• Material Science Research: Utilized in the creation of advanced organic frameworks and functional materials.
• Academic & Industrial R&D: A versatile reagent for methodological studies in organic chemistry and process development.

Basic Information

Product Name	1,2-Cyclobutanedicarbonyl Dichloride, 1,2-Dimethyl-, trans- (9Ci)
CAS No.	97424-87-8
Molecular Formula	C8H10Cl2O2
Molecular Weight	209.07 g/mol
Synonyms	trans-1,2-Dimethyl-1,2-cyclobutanedicarbonyl dichloride; (1R,2R)-rel-1,2-Dimethylcyclobutane-1,2-dicarbonyl dichloride; 1,2-Dimethylcyclobutane-1,2-dicarboxylic acid dichloride, trans-; trans-1,2-Dimethylcyclobutane-1,2-dicarboxylic Acid Chloride; Cyclobutane-1,2-dicarbonyl dichloride, 1,2-dimethyl-, trans-
EINECS	Contact for details

Quality Control

Our 1,2-Cyclobutanedicarbonyl Dichloride, 1,2-Dimethyl-, trans- (9Ci) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity analysis by HPLC and GC, to ensure it meets the high standards required for pharmaceutical and fine chemical applications. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and reacts with water and alcohols; ensure containers are sealed under an inert atmosphere (e.g., nitrogen or argon) after opening. Keep away from strong bases, amines, and oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC/GC)	≥ 97.0% (Area %)
Chiral Purity (Chiral HPLC)	≥ 99.0% de (diastereomeric excess)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.