Description

Guanosine, Guanylyl-(3'->5')-, Monoammonium Salt is a high-purity nucleotide derivative, essential for biochemical research and pharmaceutical development. This compound serves as a critical building block and substrate in enzymatic studies, particularly those involving RNA synthesis and modification. It is primarily utilized by researchers in molecular biology, enzymology, and by manufacturers developing diagnostic kits and therapeutic oligonucleotides.

Application

• Enzymatic Synthesis Substrate: Used as a key substrate for RNA ligases, polymerases, and capping enzymes in in vitro transcription and RNA synthesis applications.
• Biochemical Research: Essential for studying enzyme kinetics, mechanism of action, and inhibition profiles of nucleotidyltransferases and related enzymes.
• Diagnostic Reagent Manufacturing: Incorporated into the production of labeled probes and primers for molecular diagnostics and next-generation sequencing (NGS) platforms.
• Therapeutic Oligonucleotide Development: Acts as a raw material in the research and development of novel antisense oligonucleotides, siRNA, and mRNA-based therapeutics.
• Reference Standard: Serves as a high-purity analytical standard for quality control in pharmaceutical and biotechnology laboratories.

Basic Information

Product Name	Guanosine, Guanylyl-(3'->5')-, Monoammonium Salt
CAS No.	97403-87-7
Molecular Formula	C20H29N10O12P2 • xNH3
Molecular Weight	Contact for details
Synonyms	Guanosine 5'-monophosphate, 3'-5'-cyclic, monoammonium salt; GpG monoammonium salt; Guanylyl(3'-5')guanosine monoammonium salt; P1,P2-Di(guanosine-5') triphosphate, ammonium salt; Guanosine 5'-(trihydrogen diphosphate), 5'-5' ester with guanosine, ammonium salt; Diguanylic acid ammonium salt; Guanosine 3',5'-cyclic monophosphate guanylyl (3'->5') guanosine monoammonium salt
EINECS	Contact for details

Quality Control

Our Guanosine, Guanylyl-(3'->5')-, Monoammonium Salt is produced under stringent quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the exacting standards required for life science research. A Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This material is hygroscopic (moisture-sensitive). Allow the sealed container to equilibrate to room temperature before opening to minimize moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/UV)	Conforms
Purity (HPLC)	≥ 95%
Assay	≥ 85% (anhydrous basis)
Water Content (KF)	≤ 10%
Ammonium Content	Conforms
Solubility	Soluble in water

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.