Description

4-Chloro-7-(2-Deoxy--D-Ribofuranosyl)-7H-Pyrrolo[2,3-D]-Pyrimidine CAS NO 97337-37-6 is a high-purity nucleoside analog building block of significant importance in advanced pharmaceutical research and development. This compound serves as a critical synthetic intermediate for the creation of novel antiviral and anticancer agents, particularly in the field of nucleoside-based therapeutics. It is primarily utilized by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers engaged in the synthesis of modified oligonucleotides and targeted drug candidates.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel nucleoside analog drugs targeting viral infections and oncology.
• Antiviral Drug Development: Used in R&D for prodrugs and active pharmaceutical ingredients (APIs) against a range of viruses.
• Anticancer Agent Research: Serves as a precursor in the development of chemotherapeutic compounds that interfere with DNA/RNA synthesis.
• Oligonucleotide Synthesis: Employed in the preparation of modified DNA/RNA sequences for therapeutic and diagnostic applications.
• Biochemical Research: Utilized as a substrate or inhibitor in enzymatic studies and molecular biology research.
• Process Chemistry & Scale-Up: Sourced by fine chemical manufacturers for cGMP and non-GMP production of advanced intermediates.

Basic Information

Product Name	4-Chloro-7-(2-Deoxy--D-Ribofuranosyl)-7H-Pyrrolo[2,3-D]-Pyrimidine
CAS No.	97337-37-6
Molecular Formula	C11H12ClN3O4
Molecular Weight	285.68 g/mol
Synonyms	4-Chloro-7-(2-deoxy-β-D-ribofuranosyl)-7H-pyrrolo[2,3-d]pyrimidine; 4-Chloro-7-(2-deoxy-β-D-erythro-pentofuranosyl)-7H-pyrrolo[2,3-d]pyrimidine; 4-Chloro-7-(2-deoxy-β-D-ribosyl)-7H-pyrrolo[2,3-d]pyrimidine; 4-Chlorotubercidin derivative; 7-(2-Deoxy-β-D-ribofuranosyl)-4-chloro-7H-pyrrolo[2,3-d]pyrimidine; 4-Cl-7-(2'-deoxyribosyl)-7H-pyrrolo[2,3-d]pyrimidine; 4-Chloro-2'-deoxytubercidin analog
EINECS	Contact for details

Quality Control

Our 4-Chloro-7-(2-Deoxy--D-Ribofuranosyl)-7H-Pyrrolo[2,3-D]-Pyrimidine is produced under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and pharmaceutical applications. All materials are accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles as determined by advanced analytical techniques including HPLC, NMR, and mass spectrometry. We support compliance with relevant guidelines for advanced pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed in a desiccated environment and handled under appropriate conditions to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.