Description

7-Deaza-2'-Deoxyinosine is a modified nucleoside analog of significant interest in advanced biochemical research and pharmaceutical development. This compound serves as a critical building block and research tool for studying nucleic acid structure, function, and for the development of novel therapeutic agents. It is primarily utilized by research institutions, diagnostic developers, and pharmaceutical companies engaged in antiviral drug discovery, oligonucleotide synthesis, and molecular biology applications. The high-purity material is essential for ensuring reliable and reproducible experimental and production outcomes.

Application

• Antiviral Nucleoside Analogue Research: Investigated as a precursor or active component in the development of novel antiviral therapeutics.
• Oligonucleotide Synthesis: Used as a modified phosphoramidite building block for incorporating unique properties into synthetic DNA/RNA strands.
• Biochemical & Enzymatic Studies: Serves as a substrate or inhibitor for enzymes like nucleoside kinases and polymerases to study mechanism and kinetics.
• Diagnostic Probe Development: Employed in the design of fluorescent or labeled probes for genetic testing and detection assays.
• Medicinal Chemistry: A key intermediate for the synthesis of more complex nucleoside-based drug candidates.
• Academic & Industrial R&D: Fundamental research tool in molecular biology, virology, and structural biology laboratories.

Basic Information

Product Name	7-Deaza-2'-Deoxyinosine
CAS No.	97224-58-3
Molecular Formula	C11H13N4O4
Molecular Weight	265.25 g/mol
Synonyms	7-Deaza-2'-deoxyguanosine; 2'-Deoxy-7-deazaguanosine; 2'-Deoxynebularine; 7-Deaza-dG; 7-Cyano-7-deaza-2'-deoxyguanosine; 7-Deaza-2'-deoxyguanosine; 2-Amino-7-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,7-dihydropyrrolo[2,3-d]pyrimidin-4-one
EINECS	Contact for details

Quality Control

Our 7-Deaza-2'-Deoxyinosine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and development. Each lot undergoes rigorous analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and tests for residual solvents and moisture. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.