Description

3-Thiophenecarbonyl Chloride, 4-Methyl-5-Nitro- (9Ci) is a specialized heterocyclic building block and key acyl chloride intermediate. This compound matters for its role in synthesizing complex molecules, particularly in pharmaceutical research and advanced material science. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing novel thiophene-based derivatives.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially those containing functionalized thiophene cores for therapeutic applications.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides that leverage the thiophene moiety for biological activity.
• Material Science Research: Serves as a building block for creating advanced organic materials, such as organic semiconductors, conductive polymers, and non-linear optical (NLO) materials.
• Ligand and Catalyst Development: Employed in the preparation of specialized ligands for metal catalysis or as a scaffold for catalyst design in organic synthesis.
• Dye and Pigment Intermediate: Utilized in the synthesis of complex heterocyclic dyes and pigments where the nitro and carbonyl chloride groups allow for further functionalization.
• Custom Synthesis and Contract Manufacturing: A critical reagent for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) producing bespoke chemicals for client projects.

Basic Information

Item	Detail
Product Name	3-Thiophenecarbonyl Chloride, 4-Methyl-5-Nitro- (9Ci)
CAS No.	97187-90-1
Molecular Formula	C6H4ClNO3S
Molecular Weight	205.62 g/mol
Synonyms	4-Methyl-5-nitrothiophene-3-carbonyl chloride; 5-Nitro-4-methylthiophene-3-carbonyl chloride; 4-Methyl-5-nitro-3-thiophenecarbonyl chloride; 3-Carbonyl chloride-4-methyl-5-nitrothiophene; 4-Methyl-5-nitrothiophene-3-carboxylic acid chloride
EINECS	Contact for details

Quality Control

Every batch of 3-Thiophenecarbonyl Chloride, 4-Methyl-5-Nitro- (9Ci) is produced and tested under strict quality management protocols to ensure consistency and reliability for your synthetic workflows. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as purity (by HPLC/NMR), identity confirmation, and impurity profiles. Our quality systems are designed to support cGMP and ISO standards for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) to prevent decomposition. Keep away from strong bases, oxidizing agents, and sources of ignition.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.