Description

9-((1,3-Dihydroxy-2-Propylthio)Methyl)Guanine is a high-purity nucleoside analogue derivative with significant research and pharmaceutical development potential. This compound serves as a critical intermediate in the synthesis of novel antiviral and anticancer agents, offering a versatile scaffold for medicinal chemistry. It is primarily utilized by pharmaceutical R&D laboratories, academic research institutions, and fine chemical manufacturers focused on developing next-generation therapeutics.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel antiviral and anticancer nucleoside analogues.
• Biochemical Research: Used in enzymatic studies and as a substrate analog to investigate nucleotide metabolism pathways.
• Medicinal Chemistry: Serves as a core scaffold for structure-activity relationship (SAR) studies to optimize drug potency and selectivity.
• Antiviral Agent Development: Investigated for its potential activity against DNA viruses, including herpesviruses and hepatitis B virus (HBV).
• Reference Standard: Employed as a certified reference material (CRM) for analytical method development and quality control in pharmaceutical analysis.
• Preclinical Studies: Utilized in *in vitro* and *in vivo* models to evaluate pharmacokinetics, toxicity, and efficacy profiles.

Basic Information

Product Name	9-((1,3-Dihydroxy-2-Propylthio)Methyl)Guanine
CAS No.	97151-23-0
Molecular Formula	C9H15N5O3S
Molecular Weight	273.31 g/mol
Synonyms	9-[(1,3-Dihydroxy-2-propylthio)methyl]guanine; 9-((1,3-Dihydroxy-2-propylthio)methyl)guanine; 2-Amino-9-[(1,3-dihydroxy-2-propylthio)methyl]-1,9-dihydro-6H-purin-6-one; Ganciclovir intermediate; DHPG derivative; 9-(1,3-Dihydroxy-2-propoxymethyl)guanine analog; NSC 629153
EINECS	Contact for details

Quality Control

Our 9-((1,3-Dihydroxy-2-Propylthio)Methyl)Guanine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and stringent controls for residual solvents and impurities. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to ensure traceability and compliance with your research or cGMP requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.