Description

Corticosterone 21-Stearate is a specific ester derivative of the endogenous glucocorticoid corticosterone. This compound is of significant interest in pharmaceutical research and development, particularly for studying steroid metabolism and as a potential synthetic intermediate for more complex steroid-based molecules. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel therapeutic agents, analytical method development, and biochemical studies related to adrenal function and stress response pathways.

Application

• Pharmaceutical Research & Development: Serves as a key reference standard and synthetic intermediate in the development of novel corticosteroid-based therapeutics.
• Biochemical Studies: Used in metabolic pathway research to investigate the esterification and hydrolysis of steroid hormones.
• Analytical Chemistry: Employed as a high-purity standard for method development and validation in chromatographic analysis (HPLC, LC-MS) of steroid compounds.
• Endocrinology Research: A tool compound for studying the structure-activity relationships (SAR) of glucocorticoid receptor ligands and their prodrug formulations.
• Academic Research: Utilized in university and institutional labs for fundamental studies in steroid chemistry and pharmacology.

Basic Information

Product Name	Corticosterone 21-Stearate
CAS No.	96887-49-9
Molecular Formula	C39H64O5
Molecular Weight	613.0 g/mol (approx.)
Synonyms	11-Dehydrocorticosterone 21-stearate; Corticosterone 21-octadecanoate; 21-Stearoyloxycorticosterone; Pregn-4-ene-3,11,20-trione, 21-(1-oxooctadecyl)oxy]-; (11β)-21-(Stearoyloxy)pregn-4-ene-3,11,20-trione
EINECS	Contact for details

Quality Control

Our Corticosterone 21-Stearate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including identification by spectroscopic methods (IR, NMR) and purity assessment by HPLC to ensure it meets exacting standards for research use. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and other critical parameters.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as indicated on the label. This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.