Description

Nourseothricin Sulfate is a potent aminoglycoside antibiotic complex derived from *Streptomyces noursei*. Its primary value lies in its broad-spectrum antibacterial activity, making it a critical selective agent in molecular biology and biotechnology. This product is essential for researchers and manufacturers in the pharmaceutical and life science industries, particularly for applications requiring robust selection pressure in cell culture and genetic engineering workflows. Nourseothricin Sulfate CAS NO 96736-11-7 is supplied as a high-purity reagent to ensure consistent and reliable performance.

Application

• Selective Agent in Molecular Biology: Widely used for the selection and maintenance of prokaryotic and eukaryotic cells transfected with resistance genes (e.g., nat1, nourseothricin acetyltransferase).
• Microbiological Research: Employed in studies of bacterial physiology, antibiotic resistance mechanisms, and as a tool compound in antimicrobial discovery.
• Biopharmaceutical Production: Utilized in the development and manufacturing of recombinant proteins and viral vectors, where stable, antibiotic-selected producer cell lines are required.
• Plant Biotechnology: Applied as a selective agent in the transformation and regeneration of genetically modified plants.
• Fungal Genetics: Serves as a selection marker in yeast and other fungal systems for genetic manipulation and functional genomics.
• Veterinary Medicine: Historically used and studied for its efficacy against certain Gram-positive and Gram-negative bacterial infections in animals.

Basic Information

Product Name	Nourseothricin Sulfate
CAS No.	96736-11-7
Molecular Formula	C31H59N7O17 • xH2SO4
Molecular Weight	~712.7 (for base, variable with sulfate content)
Synonyms	Streptothricin Sulfate; Nourseothricin; Antibiotic SF-767; Antibiotic A-469; Streptolin; Framycetin (related complex); Polyaminoglycoside antibiotic; BRN 4618967
EINECS	Contact for details

Quality Control

Our Nourseothricin Sulfate is manufactured and tested under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure high purity, potency, and consistency suitable for research and bioproduction applications. Certificates of Analysis (COA) detailing purity, assay, microbiological potency, and impurity profiles are provided and available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C for long-term stability. This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent absorption of atmospheric moisture.

Specification

Item	Specification
Appearance	White to yellowish powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 95.0% (on anhydrous basis)
Potency (Microbiological)	≥ 800 µg/mg
pH (1% Solution)	4.0 - 6.0
Water (Karl Fischer)	≤ 5.0 %
Residue on Ignition	≤ 1.0 %
Bacterial Endotoxins	< 1.0 EU/mg (where specified)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.