Description

3'-(3-(2-Chloroethyl)-3-Nitrosoureido)-2',3'-Dideoxy-5-Fluorouridine is a specialized nucleoside analog derivative that serves as a critical intermediate in advanced pharmaceutical research and development. This compound is valued for its potential role in the synthesis of novel chemotherapeutic agents and antiviral drugs, offering researchers a pathway to explore new mechanisms of action. It is primarily sought by pharmaceutical R&D laboratories, biotechnology companies, and academic institutions focused on oncology and virology. The precise molecular architecture of this intermediate allows for targeted modifications in drug discovery programs aiming to improve therapeutic efficacy and selectivity.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of experimental nucleoside-based chemotherapeutic agents.
• Anticancer Research: Used in R&D for developing prodrugs and targeted therapies that leverage its modified uridine structure.
• Antiviral Drug Development: Serves as a precursor in the creation of novel compounds designed to inhibit viral replication.
• Biochemical Probe: Utilized in mechanistic studies to understand cell cycle inhibition and apoptosis pathways.
• Preclinical Studies: Employed in the formulation and testing of new drug candidates in laboratory settings.
• Process Chemistry: Acts as a standard or reference material in scaling up synthetic routes for active pharmaceutical ingredients (APIs).

Basic Information

Product Name	3'-(3-(2-Chloroethyl)-3-Nitrosoureido)-2',3'-Dideoxy-5-Fluorouridine
CAS No.	96699-71-7
Molecular Formula	C12H15ClFN4O6
Molecular Weight	374.72 g/mol
Synonyms	5-Fluoro-2',3'-dideoxy-3'-[N-(2-chloroethyl)-N-nitrosoureido]uridine; 3'-[(2-Chloroethyl)nitrosocarbamoyl]-2',3'-dideoxy-5-fluorouridine; 3'-(3-(2-Chloroethyl)-3-nitrosoureido)-2',3'-dideoxy-5-fluorouridine; 5-Fluoro-3'-[(2-chloroethyl)nitrosoureido]-2',3'-dideoxyuridine; 2',3'-Dideoxy-5-fluoro-3'-[(2-chloroethyl)nitrosoureido]uridine; 3'-Deoxy-5-fluoro-3'-[(2-chloroethyl)nitrosoureido]uridine (ambiguous); FCddUrd-Nitrosourea derivative
EINECS	Contact for details

Quality Control

Our 3'-(3-(2-Chloroethyl)-3-Nitrosoureido)-2',3'-Dideoxy-5-Fluorouridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity assessment and spectroscopic methods for structural confirmation, to ensure it meets the high standards required for research applications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request to support your regulatory and quality assurance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This product is light-sensitive (store away from light). For long-term storage, consider keeping the material under inert atmosphere to maximize stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.