Description

Icrf 158 is a bis-dioxopiperazine derivative and a potent chelating agent with significant research interest. This compound, identified by CAS No. 1155-54-0, is primarily valued for its role as a key intermediate in the synthesis of more complex pharmaceutical agents and as a biochemical tool in metalloenzyme research. It is essential for research and development laboratories in the pharmaceutical, biotechnology, and academic sectors focusing on oncology, cardiology, and chelation therapy studies.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of investigational cardioprotective and antineoplastic agents.
• Biochemical Research: Used as a selective chelator in studies of iron-dependent enzymes and metabolic pathways.
• Reference Standard: Employed as an analytical standard in quality control laboratories for method development and validation.
• Academic Research: Utilized in university and institutional labs for fundamental studies on metal chelation and its biological effects.
• Preclinical Development: Acts as a tool compound in drug discovery programs targeting oxidative stress and metal overload.

Basic Information

Product Name	Icrf 158
CAS No.	1155-54-0
Molecular Formula	C11H14N4O4
Molecular Weight	266.25 g/mol
Synonyms	ICRF-158; (+)-1,2-Bis(3,5-dioxopiperazin-1-yl)propane; Razoxane Impurity; NSC-129,943; Dexrazoxane Impurity; Bisdioxopiperazine; 1,2-Bis(3,5-dioxopiperazin-1-yl)propane; ICRF 158
EINECS	214-560-6

Quality Control

Our Icrf 158 is manufactured under a quality management system and undergoes rigorous analytical testing to ensure identity, purity, and consistency. Standard quality parameters include assay by HPLC, identification by FT-IR, and control of related substances. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with each batch to support your research and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.