Description

Tacedinaline is a potent and selective histone deacetylase (HDAC) inhibitor, a compound of significant interest in pharmaceutical research and development. Its primary value lies in its ability to modulate gene expression and induce cell differentiation and apoptosis, making it a crucial tool for investigating epigenetic mechanisms and therapeutic pathways. This compound is essential for researchers and developers in the fields of oncology, neurology, and epigenetics, particularly for preclinical studies targeting cancer and neurodegenerative diseases. Tacedinaline CAS NO 112522-64-2 represents a high-purity research chemical for advancing innovative drug discovery programs.

Application

• Oncology Research: Investigated as a potential therapeutic agent for various cancers, including leukemia, breast, and prostate cancer, due to its HDAC inhibitory activity.
• Neurodegenerative Disease Studies: Used in research models for conditions like Alzheimer's and Huntington's disease to explore the role of histone acetylation in neuroprotection and cognitive function.
• Epigenetics & Molecular Biology: Serves as a critical research tool for studying chromatin remodeling, gene silencing, and cellular differentiation pathways in vitro and in vivo.
• Pharmaceutical Reference Standard: Employed as a high-purity analytical standard for method development, quality control, and pharmacokinetic studies in drug development pipelines.
• Biochemical Assay Development: Utilized in screening assays to identify and characterize new HDAC inhibitors or to validate assay systems for epigenetic drug discovery.

Basic Information

Product Name	Tacedinaline
CAS No.	112522-64-2
Molecular Formula	C17H19N3O4
Molecular Weight	329.35 g/mol
Synonyms	CI-994; N-Acetyldinaline; PD 123654; Goe 5549; 4-(Acetylamino)-N-(2-aminophenyl)benzamide; NSC 610226; Acetyldinaline
EINECS	Contact for details

Quality Control

Our Tacedinaline is manufactured under strict quality management systems to ensure the highest standards of purity and consistency, suitable for sensitive research applications. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry guidelines, and our quality protocols are designed to meet the stringent requirements of pharmaceutical reference standards and preclinical research materials. Certificates of Analysis (COA) are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥98.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Related Substances (HPLC)	Individual impurity ≤0.5%; Total impurities ≤2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.