Description

4-Azidosalicylic Acid n-Hydroxysuccinimide Ester is a specialized heterobifunctional crosslinking reagent that combines a photoactivatable aryl azide group with an amine-reactive NHS ester. This compound matters for researchers and manufacturers requiring efficient, light-induced conjugation of biomolecules, enabling the study of protein interactions, surface immobilization, and the development of diagnostic assays. It is primarily needed by professionals in the fields of bioconjugation, proteomics, and advanced materials science for creating stable covalent linkages under mild conditions.

Application

• Photoaffinity labeling of proteins and other biomolecules for interaction studies.
• Surface functionalization and immobilization of proteins, peptides, or antibodies on chips, beads, or biosensors.
• Crosslinking agent in the synthesis of polymer-protein conjugates or biomaterial scaffolds.
• Probe development for studying receptor-ligand interactions in biochemical research.
• Tool compound in proteomics for capturing transient or weak protein complexes.
• Modification of nucleic acids or oligonucleotides for advanced diagnostic applications.

Basic Information

Product Name	4-Azidosalicylic Acid n-Hydroxysuccinimide Ester
CAS No.	96602-46-9
Molecular Formula	C11H7N4O5
Molecular Weight	275.20 g/mol
Synonyms	4-Azidosalicylic Acid NHS Ester; 5-Azido-2-hydroxybenzoic Acid N-Hydroxysuccinimide Ester; 4-Azido-2-hydroxybenzoic Acid Succinimidyl Ester; ASH NHS Ester; NHS-Azido-Salicylate; N-Succinimidyl 4-Azidosalicylate; 4-Azidosalicyloyloxysuccinimide; 96602-46-9
EINECS	Contact for details

Quality Control

Our 4-Azidosalicylic Acid n-Hydroxysuccinimide Ester is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under desiccant. This compound is hygroscopic (moisture-sensitive) and light-sensitive. Allow the vial to equilibrate to room temperature in a dry environment before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 1.0%
Solubility	Soluble in DMF, DMSO, acetonitrile

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.