Description

2,6-Dichloro-5-Fluoronicotinoyl Chloride is a high-value, multi-functional chemical intermediate essential for modern synthetic chemistry. Its core value lies in its reactive acid chloride group and halogenated pyridine structure, enabling precise and efficient construction of complex molecules. This compound is critically needed by research institutions and manufacturers in the pharmaceutical and agrochemical industries for developing new active ingredients.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in fluorinated drug candidates.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides, leveraging its halogenated nicotinoyl scaffold.
• Material Science Research: Serves as a precursor for creating specialized polymers and liquid crystals with unique properties.
• Organic Synthesis: A versatile reagent for amide bond formation and the introduction of the 2,6-dichloro-5-fluoronicotinoyl moiety into target molecules.
• Chemical Reference Standard: Utilized as a high-purity standard in analytical laboratories for method development and quality control.

Basic Information

Product Name	2,6-Dichloro-5-Fluoronicotinoyl Chloride
CAS No.	96568-02-4
Molecular Formula	C7H2Cl3FNO
Molecular Weight	248.45 g/mol
Synonyms	5-Fluoro-2,6-dichloronicotinoyl chloride; 2,6-Dichloro-5-fluoropyridine-3-carbonyl chloride; 3-Pyridinecarbonyl chloride, 2,6-dichloro-5-fluoro-; 96568-02-4; 5-Fluoro-2,6-dichloronicotinic acid chloride; 2,6-Dichloro-5-fluoro-3-pyridinecarbonyl chloride
EINECS	Contact for details

Quality Control

Our 2,6-Dichloro-5-Fluoronicotinoyl Chloride is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure high purity and consistency. Certificates of Analysis (COA) detailing all specifications are provided with each shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic (moisture-sensitive) nature and reactivity as an acid chloride, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent degradation. Recommended storage temperature is 2-8°C for long-term stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.