Description

n-(3-Isobutyl-9,10-Dimethoxy-1,2,3,4,6,7-Hexahydro-11Bh-Benzo(A)Quinolizin-2-Yl)-4-((4-Azido-2-Nitrophenyl)Amino)Butanamide is a sophisticated synthetic organic compound featuring a complex benzoquinolizine core structure integrated with an azido-nitrophenyl functional group. This compound is of significant value in advanced research and development, particularly for its potential as a specialized intermediate or a photoaffinity labeling probe due to the reactive azide moiety. It is primarily sought after by pharmaceutical R&D laboratories, academic research institutions, and specialty chemical manufacturers engaged in medicinal chemistry, chemical biology, and proteomics studies. The compound, with CAS NO 96557-41-4, requires expert handling to preserve its integrity for critical applications.

Application

• Photoaffinity Labeling Probe: Utilized in chemical biology and proteomics research to covalently capture and identify protein-ligand interactions upon photoactivation.
• Medicinal Chemistry Intermediate: Serves as a key building block in the synthesis of novel drug candidates targeting complex biological pathways.
• Bioconjugation Reagent: Employed for the site-specific modification of biomolecules (e.g., proteins, antibodies) via click chemistry or other bioorthogonal reactions.
• Chemical Biology Research: Used in the development of activity-based probes (ABPs) for enzyme profiling and target identification studies.
• High-Throughput Screening (HTS): Acts as a specialized component in screening libraries for drug discovery campaigns.
• Academic & Institutional Research: Fundamental tool for investigating reaction mechanisms and developing new synthetic methodologies in organic chemistry.

Basic Information

Product Name	n-(3-Isobutyl-9,10-Dimethoxy-1,2,3,4,6,7-Hexahydro-11Bh-Benzo(A)Quinolizin-2-Yl)-4-((4-Azido-2-Nitrophenyl)Amino)Butanamide
CAS No.	96557-41-4
Molecular Formula	C29H37N7O5
Molecular Weight	563.65 g/mol
Synonyms	4-((4-Azido-2-nitrophenyl)amino)-N-[3-(2-methylpropyl)-9,10-dimethoxy-1,2,3,4,6,7-hexahydro-11bH-benzo[a]quinolizin-2-yl]butanamide; Benzo[a]quinolizine-2-butanamide derivative; 96557-41-4; Azido-nitrophenyl benzoquinolizine amide; Photoaffinity labeling agent 96557-41-4; Aryl azide functionalized benzoquinolizine.
EINECS	Contact for details

Quality Control

Our production of n-(3-Isobutyl-9,10-Dimethoxy-1,2,3,4,6,7-Hexahydro-11Bh-Benzo(A)Quinolizin-2-Yl)-4-((4-Azido-2-Nitrophenyl)Amino)Butanamide adheres to stringent quality protocols to ensure batch-to-batch consistency and reliability for sensitive research applications. Each lot undergoes comprehensive analytical characterization, including HPLC for purity, NMR and MS for structural confirmation, and functional group integrity checks. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes. We support research under GMP/GLP guidelines and can tailor specifications to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) in a dedicated freezer. The compound is strictly light-sensitive (protect from all light exposure) and easily oxidized (store under inert atmosphere). Allow the sealed container to equilibrate to room temperature before opening to prevent moisture condensation. Keep away from heat, sparks, and open flames.

Specification

Item	Specification
Appearance	Yellow to orange solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.