Description

5-(tert-Butyl)-2-Methylfuran-3-Carbonyl Chloride is a highly reactive and versatile acyl chloride derivative, serving as a critical building block in advanced organic synthesis. Its core value lies in enabling the efficient introduction of the sterically hindered 5-(tert-butyl)-2-methylfuran-3-carbonyl moiety, a key structural motif for modifying molecular properties. This compound is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key reagent for the synthesis of novel drug candidates, particularly in creating amide and ester derivatives for targeted therapies.
• Agrochemical Synthesis: Used in the production of advanced fungicides, herbicides, and insecticides where the furan ring contributes to biological activity.
• Material Science Precursor: Acts as a monomer or cross-linking agent in the development of specialized polymers and functional coatings.
• Ligand and Catalyst Development: Employed to synthesize complex organic ligands for metal catalysis and asymmetric synthesis.
• Chemical Research & Development: A fundamental tool in academic and industrial R&D for exploring new chemical entities and reaction pathways.
• Fine Chemical Production: Integral to the multi-step synthesis of complex fragrance, flavor, and dye intermediates.

Basic Information

Product Name	5-(tert-Butyl)-2-Methylfuran-3-Carbonyl Chloride
CAS No.	96543-75-8
Molecular Formula	C10H13ClO2
Molecular Weight	200.66 g/mol
Synonyms	5-tert-Butyl-2-methyl-3-furoyl chloride; 3-Furoyl chloride, 5-(1,1-dimethylethyl)-2-methyl-; 2-Methyl-5-tert-butylfuran-3-carbonyl chloride; 5-(1,1-Dimethylethyl)-2-methyl-3-furoyl chloride; 5-tert-Butyl-2-methylfuran-3-carboxylic acid chloride
EINECS	Contact for details

Quality Control

Our production of 5-(tert-Butyl)-2-Methylfuran-3-Carbonyl Chloride adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity for demanding synthetic applications. Each lot undergoes comprehensive analytical testing, including HPLC for assay and impurity profiling, NMR for structural confirmation, and Karl Fischer titration for moisture content. A detailed Certificate of Analysis (COA) documenting all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic and moisture-sensitive nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) when not in use to prevent decomposition. Keep away from strong bases, oxidizing agents, and sources of ignition.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.