Description

11β,17,20β,21-Tetrahydroxypregna-1,4-Dien-3-One 21-Acetate is a high-purity synthetic steroid derivative, specifically a 21-acetate ester of a tetrahydroxylated pregnadiene. This compound is valued as a critical pharmaceutical intermediate and reference standard in research and development. It is primarily required by manufacturers and R&D laboratories in the pharmaceutical, biotechnology, and fine chemical synthesis sectors for the production and analysis of advanced steroid-based therapeutics.

Application

• Pharmaceutical Intermediate: A key building block in the multi-step synthesis of complex corticosteroid drugs and other bioactive steroid molecules.
• Reference Standard: Used in analytical laboratories for method development, validation, and quality control (QC) testing of related pharmaceutical products via HPLC, LC-MS, or NMR.
• Biochemical Research: Serves as a precursor or tool compound in metabolic pathway studies, receptor binding assays, and steroid hormone research.
• Process Development: Employed in scaling up and optimizing synthetic routes for steroid manufacturing within GMP environments.
• Custom Synthesis: A starting material for the preparation of novel steroid analogs with potential therapeutic applications in anti-inflammatory or endocrine treatments.

Basic Information

Product Name	11β,17,20β,21-Tetrahydroxypregna-1,4-Dien-3-One 21-Acetate
CAS No.	96346-38-2
Molecular Formula	C23H32O6
Molecular Weight	404.50 g/mol
Synonyms	21-Acetoxy-11β,17,20β,21-tetrahydroxypregna-1,4-dien-3-one; 11β,17,20β,21-Tetrahydroxypregna-1,4-diene-3,20-dione 21-acetate; Pregna-1,4-diene-3,20-dione, 11,17,20,21-tetrahydroxy-, 21-acetate, (11β,20β)-; 11β,17α,20β,21-Tetrahydroxypregna-1,4-dien-3-one 21-acetate; 11β,17,20β,21-Tetrahydroxy-1,4-pregnadiene-3,20-dione 21-acetate
EINECS	Contact for details

Quality Control

Our 11β,17,20β,21-Tetrahydroxypregna-1,4-Dien-3-One 21-Acetate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, identity confirmation (IR, NMR), and residual solvent analysis, to ensure it meets stringent specifications for pharmaceutical R&D and intermediate use. A detailed Certificate of Analysis (COA) is provided with every shipment to guarantee traceability and compliance with your project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.