Description

Imidazo4,5-D1,3Diazepin-8-Ol, 3-(2-Chloro-2-Deoxy-.Beta.-D-Ribofuranosyl)-3,4,7,8-Tetrahydro-, (8R)- is a sophisticated nucleoside analog with significant potential in advanced pharmaceutical research and development. This compound is valued for its unique structural framework, which combines an imidazodiazepine core with a modified ribose sugar moiety, making it a critical intermediate for exploring novel therapeutic pathways. It is primarily sought by research institutions and pharmaceutical companies engaged in the synthesis of antiviral agents, anticancer drug candidates, and other high-value specialty chemicals. The compound, identified by CAS No. 96328-17-5, demands expert handling and high-purity synthesis to ensure research integrity and reproducible results.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the research and synthesis of novel antiviral and anticancer drug candidates.
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies and mechanism-of-action research for nucleoside-processing enzymes.
• Medicinal Chemistry: A valuable scaffold for structure-activity relationship (SAR) studies to optimize potency and selectivity of new chemical entities.
• Preclinical Development: Employed in the production of compounds for in vitro and in vivo biological testing and toxicology studies.
• Reference Standard: Utilized as a high-purity analytical standard for quality control and method development in analytical laboratories.
• Academic Research: Facilitates groundbreaking studies in organic synthesis, chemical biology, and drug discovery at universities and R&D centers.

Basic Information

Product Name	Imidazo4,5-D1,3Diazepin-8-Ol, 3-(2-Chloro-2-Deoxy-.Beta.-D-Ribofuranosyl)-3,4,7,8-Tetrahydro-, (8R)-
CAS No.	96328-17-5
Molecular Formula	C12H15ClN4O4
Molecular Weight	314.73 g/mol
Synonyms	(8R)-3-(2-Chloro-2-deoxy-β-D-ribofuranosyl)-3,4,7,8-tetrahydroimidazo[4,5-d][1,3]diazepin-8-ol; 2'-Chloro-2'-deoxy-β-D-ribofuranosylimidazo[4,5-d][1,3]diazepin-8-ol (8R isomer); 96328-17-5; Imidazo[4,5-d][1,3]diazepin-8-ol, 3-(2-chloro-2-deoxy-β-D-ribofuranosyl)-3,4,7,8-tetrahydro-, (8R)-; Chlorinated imidazodiazepine nucleoside
EINECS	Contact for details

Quality Control

Every batch of Imidazo4,5-D1,3Diazepin-8-Ol, 3-(2-Chloro-2-Deoxy-.Beta.-D-Ribofuranosyl)-3,4,7,8-Tetrahydro-, (8R)- is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and structural identity suitable for research applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container should be kept in a desiccated environment. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Assay	≥ 97.0% (on anhydrous basis)
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.