Description

n-(2,3-Dihydro-1H-Inden-1-Yl)Adenosine is a chemically modified nucleoside derivative, specifically an adenosine analog with an indane substituent. This structural modification is of significant interest in medicinal chemistry for the development of novel therapeutic agents targeting adenosine receptors. It serves as a critical pharmaceutical intermediate and a valuable research chemical for biochemical studies. This compound is primarily utilized by research institutions and pharmaceutical companies engaged in drug discovery, particularly for cardiovascular and neurological applications.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel adenosine receptor agonists and antagonists.
• Biochemical Research: Used as a ligand or probe in receptor binding assays and signal transduction studies.
• Medicinal Chemistry: Serves as a core scaffold for structure-activity relationship (SAR) studies to optimize drug candidates.
• Cardiovascular Research: Investigated for potential applications in modulating heart rate and coronary blood flow.
• Neuropharmacology: Explored for its effects on the central nervous system, including neuroprotection and modulation of neurotransmitter release.
• Reference Standard: Employed as an analytical standard in quality control and method development for related compounds.

Basic Information

Product Name	n-(2,3-Dihydro-1H-Inden-1-Yl)Adenosine
CAS No.	96323-20-5
Molecular Formula	C19H21N5O4
Molecular Weight	383.40 g/mol
Synonyms	1H-Inden-1-yladenosine; N-(2,3-Dihydro-1H-inden-1-yl)adenosine; Adenosine, N-(2,3-dihydro-1H-inden-1-yl)-; 1-(2,3-Dihydro-1H-inden-1-yl)adenosine; N6-(2,3-Dihydro-1H-inden-1-yl)adenosine; (1S)-N6-(2,3-Dihydro-1H-inden-1-yl)adenosine; (R)-N6-(2,3-Dihydro-1H-inden-1-yl)adenosine (if applicable); ADA (context-specific abbreviation)
EINECS	Contact for details

Quality Control

Our n-(2,3-Dihydro-1H-Inden-1-Yl)Adenosine is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and tests for residual solvents and moisture. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with research-grade specifications. For custom synthesis or specific purity requirements (e.g., >98%, >99%), please contact our technical team.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container should be kept in a desiccated environment. For long-term storage, consider storing under an inert atmosphere such as argon or nitrogen to prevent potential degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.