Description

5’-o-Trityluridine-2’,3’-Lyxo-Epoxide is a key nucleoside derivative and protected intermediate used in advanced organic synthesis. This compound is critical for researchers and manufacturers requiring high-purity building blocks for the development of modified oligonucleotides and antiviral agents. It is primarily utilized by pharmaceutical R&D teams, fine chemical producers, and academic institutions focused on nucleoside chemistry and prodrug development.

Application

• Pharmaceutical Intermediate: Serves as a crucial protected precursor in the multi-step synthesis of novel antiviral and anticancer nucleoside analogs.
• Oligonucleotide Synthesis: Used as a specialized monomer or building block for the research-scale preparation of modified RNA and DNA strands.
• Prodrug Development: Acts as a key starting material for creating prodrugs designed to improve the bioavailability and targeting of therapeutic nucleosides.
• Chemical Biology Research: Employed in studies investigating nucleic acid structure, function, and the mechanism of action of nucleoside-based drugs.
• Fine Chemical Synthesis: Utilized in custom synthesis and process development for high-value, low-volume specialty chemicals.

Basic Information

Product Name	5’-o-Trityluridine-2’,3’-Lyxo-Epoxide
CAS No.	96253-10-0
Molecular Formula	C28H26N2O6
Molecular Weight	486.52 g/mol
Synonyms	5'-O-Trityl-2',3'-anhydro-2',3'-dideoxyuridine; 2',3'-Anhydro-5'-O-trityluridine; 5'-O-(Triphenylmethyl)-2',3'-anhydro-2',3'-dideoxyuridine; 2',3'-Epoxy-5'-O-trityl-2',3'-dideoxyuridine; Uridine, 2',3'-anhydro-5'-O-trityl-; 5'-O-Trityl-2',3'-epoxy-2',3'-dideoxyuridine; TRTU-EPOXIDE
EINECS	Contact for details

Quality Control

Every batch of 5’-o-Trityluridine-2’,3’-Lyxo-Epoxide is manufactured and tested under strict quality management systems. We provide comprehensive analytical data to ensure the identity, purity, and consistency required for sensitive synthetic applications. A detailed Certificate of Analysis (COA) including HPLC purity, NMR confirmation, and chiral purity is available for each lot upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Purity (HPLC, Area%)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.