Description

(Z)-Guggulsterone CAS NO 95975-55-6 is a specific stereoisomer of the bioactive phytosterol derived from the resin of the Commiphora wightii tree. This compound is of significant commercial interest due to its role as a key reference standard and active pharmaceutical ingredient (API) in research and development. It is primarily sought by manufacturers in the pharmaceutical, nutraceutical, and cosmeceutical industries for its targeted biological activities.

Application

• Pharmaceutical Reference Standard: Used for the identification, purity testing, and quantification of guggulsterone in drug substances and finished products.
• Dietary Supplement Formulation: Incorporated as an active ingredient in weight management and cholesterol-regulating nutraceutical products.
• Biochemical Research: Serves as a critical tool in metabolic and endocrine research, particularly in studies involving nuclear receptors like FXR.
• Cosmeceutical Actives: Utilized in advanced skincare formulations for its potential anti-inflammatory and lipid-regulating properties.
• API Synthesis: Acts as a starting material or intermediate in the synthesis of more complex steroid-based therapeutic agents.
• Quality Control Laboratories: Essential for analytical method development and validation in QC/QA protocols for herbal extracts.

Basic Information

Product Name	(Z)-Guggulsterone
CAS No.	95975-55-6
Molecular Formula	C21H28O2
Molecular Weight	312.45 g/mol
Synonyms	(Z)-Guggulsterone; cis-Guggulsterone; (17Z)-Pregna-4,17-diene-3,16-dione; NSC 1668; Guggulsterone Z isomer; Commiphora mukul extract constituent
EINECS	Contact for details

Quality Control

Our (Z)-Guggulsterone is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing including HPLC for purity, identity confirmation by spectroscopic methods (IR, NMR), and residual solvent analysis. We provide full traceability and Certificates of Analysis (COA) are available for every shipment, ensuring compliance with research and cGMP-grade material requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Residual Solvents	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.