Description

Bicyclo[3.2.1]Octane-3-Carbonyl Chloride, 3-(1-Methylethyl)- (9Ci) is a specialized bicyclic organic building block featuring a reactive acid chloride functional group. This compound is valued for its unique sterically hindered structure, which is critical for introducing the bicyclo[3.2.1]octane scaffold into target molecules. It serves as a key high-purity intermediate for advanced research and development in pharmaceutical chemistry and material science. Target users include R&D chemists and process development scientists working on novel active pharmaceutical ingredients (APIs), agrochemicals, and functional materials.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of novel drug candidates, particularly those requiring complex, three-dimensional bicyclic frameworks to modulate biological activity and pharmacokinetic properties.
• Agrochemical Research: Used in the development of new pesticides and herbicides, where the bicyclic structure can contribute to unique modes of action and environmental stability.
• Material Science Precursor: Employed in the synthesis of specialty polymers, ligands for catalysis, or advanced organic frameworks (MOFs/COFs) due to its rigid molecular geometry.
• Chemical Biology Probe Synthesis: Facilitates the creation of molecular probes and labeled compounds for studying biological pathways and enzyme functions.
• Asymmetric Synthesis: Acts as a chiral starting material or intermediate for constructing complex natural products and enantiomerically pure compounds.
• Scale-up Process Development: Supplied for optimization and kilogram-scale production runs in pilot plants and commercial manufacturing.

Basic Information

Product Name	Bicyclo[3.2.1]Octane-3-Carbonyl Chloride, 3-(1-Methylethyl)- (9Ci)
CAS No.	95685-43-1
Molecular Formula	C12H17ClO
Molecular Weight	212.72 g/mol
Synonyms	3-Isopropylbicyclo[3.2.1]octane-3-carbonyl chloride; 3-(1-Methylethyl)bicyclo[3.2.1]octane-3-carbonyl chloride; 3-Isopropylbicyclo[3.2.1]octan-3-carbonyl chloride; Bicyclo[3.2.1]octane-3-carbonyl chloride, 3-(1-methylethyl)-; 95685-43-1; 3-Isopropyl-3-bicyclo[3.2.1]octanecarbonyl chloride
EINECS	Contact for details

Quality Control

Our Bicyclo[3.2.1]Octane-3-Carbonyl Chloride is produced under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC analysis, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our commitment to quality supports cGMP and ISO standards for reliable use in critical development and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic (moisture-sensitive) nature and reactivity as an acid chloride, it must be kept under an inert atmosphere (e.g., nitrogen or argon) and separated from strong bases and oxidizing agents. Recommended long-term storage temperature is 2-8°C. Allow the sealed container to reach room temperature before opening to prevent moisture condensation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.