Description

3-(Trifluoromethyl)Phenyl Chloroformate is a specialized organofluorine building block and chloroformate ester of significant industrial importance. Its core value lies in its high reactivity as an acylating and chloroformylating agent, enabling the efficient synthesis of complex molecules, particularly in advanced pharmaceutical and agrochemical research. This compound is essential for chemical manufacturers and R&D laboratories focused on developing active ingredients, fine chemicals, and functional materials. The product is supplied with a CAS registry number for precise identification and regulatory compliance.

Application

• Pharmaceutical Intermediate: Key reagent in the synthesis of active pharmaceutical ingredients (APIs), particularly for introducing the phenyl chloroformate moiety into target molecules.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides that incorporate the trifluoromethylphenyl group for enhanced bioactivity and stability.
• Polymer Chemistry: Serves as a monomer or modifying agent for creating specialty polymers with unique surface properties and chemical resistance.
• Liquid Crystal & OLED Materials: Acts as a precursor in the manufacture of fluorinated compounds for electronic display and lighting applications.
• Peptide Coupling & Protecting Groups: Employed in organic synthesis for the temporary protection of amino groups or as a coupling reagent in peptide chain assembly.
• Chemical Research & Development: A versatile building block for exploring new chemical entities in medicinal and material science research programs.

Basic Information

Product Name	3-(Trifluoromethyl)Phenyl Chloroformate
CAS No.	95668-29-4
Molecular Formula	C8H4ClF3O2
Molecular Weight	224.56 g/mol
Synonyms	m-(Trifluoromethyl)phenyl chloroformate; 3-(Trifluoromethyl)phenyl carbonochloridate; α-Trifluoro-m-tolyl chloroformate; 3-Trifluoromethylphenyl Chloroformate; (3-Trifluoromethylphenyl) chloroformate; Phenylchloroformate, 3-(trifluoromethyl)-; Chloroformic acid 3-(trifluoromethyl)phenyl ester
EINECS	Contact for details

Quality Control

Our 3-(Trifluoromethyl)Phenyl Chloroformate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, assay, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) and highly volatile nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and decomposition. Keep away from strong acids, bases, and oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Density	~1.45 g/cm³

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.