Description

2'-Deoxythymidine-5'-Diphosphate Trisodium Salt is a high-purity nucleotide derivative, essential as a critical building block and substrate in biochemical research and development. Its primary value lies in providing a reliable and consistent source of dTDP for enzymatic studies and nucleic acid synthesis. This compound is vital for researchers and manufacturers in the fields of molecular biology, enzymology, and pharmaceutical development, particularly for studying DNA polymerases and synthesizing oligonucleotides.

Application

• Enzymatic Substrate: Used as a specific substrate for DNA polymerases, reverse transcriptases, and other nucleotide-utilizing enzymes in kinetic and mechanistic studies.
• Oligonucleotide Synthesis: Serves as a key precursor in enzymatic and chemo-enzymatic routes for the synthesis of modified oligonucleotides and DNA fragments.
• Biochemical Research: Essential for in vitro studies of DNA replication, repair, and metabolism, providing a defined nucleotide source.
• Diagnostic Reagent Manufacturing: Incorporated into the production of kits and reagents for molecular diagnostics, PCR, and sequencing applications.
• Pharmaceutical Development: Utilized in the research and development of antiviral and anticancer agents that target nucleotide metabolism pathways.
• Cofactor Studies: Applied in research investigating enzymes that utilize nucleotide sugars or diphosphate-activated sugars as cofactors.

Basic Information

Product Name	2'-Deoxythymidine-5'-Diphosphate Trisodium Salt
CAS No.	95648-78-5
Molecular Formula	C10H14N2Na3O11P2
Molecular Weight	510.13 g/mol
Synonyms	dTDP Trisodium Salt; Thymidine 5'-Diphosphate Trisodium Salt; 5'-dTDP Na3; Deoxythymidine Diphosphate Trisodium; Thymidine 5'-pyrophosphate trisodium salt; dTDP-Na3; 2'-Deoxy-5'-TDP Trisodium Salt; TDP Trisodium Salt
EINECS	Contact for details

Quality Control

Our 2'-Deoxythymidine-5'-Diphosphate Trisodium Salt is manufactured under strict quality systems to ensure the high purity and consistency required for sensitive research applications. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR for structural confirmation, and ICP-MS for elemental analysis. Certificates of Analysis (COA) detailing all specifications are provided to guarantee traceability and compliance with your research or production standards.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below for long-term stability. This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment. Allow the sealed container to reach room temperature before opening to prevent condensation.

Specification

Item	Specification
Appearance	White to off-white powder or solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 5.0%
pH (5% solution)	6.0 - 8.0
Endotoxin (LAL)	< 10 EU/mg
Heavy Metals (ICP-MS)	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.