Description

2'-Deoxyinosine-5'-Triphosphate Trisodium Salt is a high-purity nucleotide analog essential for advanced molecular biology and diagnostic applications. Its primary value lies in its role as a substrate for DNA polymerases, enabling controlled incorporation into nucleic acid chains, which is critical for research accuracy and diagnostic specificity. This compound is a fundamental reagent for biotechnology companies, academic research institutions, and diagnostic kit manufacturers engaged in PCR, sequencing, and enzymatic synthesis.

Application

• Polymerase Chain Reaction (PCR): Used as a modified nucleotide substrate in specialized PCR applications, including mutagenesis and the synthesis of base-modified DNA.
• DNA Sequencing: Serves as a crucial component in next-generation sequencing (NGS) workflows and Sanger sequencing for the controlled termination of chain elongation.
• Enzymatic DNA Synthesis: Acts as a building block in enzymatic methods for the de novo synthesis of oligonucleotides and genes.
• Biochemical Research: Employed in studies of enzyme kinetics, DNA polymerase fidelity, and the mechanisms of nucleotide incorporation.
• Diagnostic Assay Development: Integral to the formulation of proprietary mixes for molecular diagnostic tests, including those for viral detection and genetic screening.
• Antiviral Drug Research: Investigated as a precursor or analog in the study of nucleoside-based antiviral compounds.

Basic Information

Product Name	2'-Deoxyinosine-5'-Triphosphate Trisodium Salt
CAS No.	95648-77-4
Molecular Formula	C10H14N4Na3O13P3
Molecular Weight	570.10 g/mol (anhydrous basis)
Synonyms	dITP Trisodium Salt; 2'-Deoxyinosine 5'-(tetrahydrogen triphosphate) trisodium salt; Deoxyinosine triphosphate trisodium salt; dITP Na3; 5'-dITP; Inosine 2'-deoxy-5'-triphosphate trisodium salt; dInoTP trisodium salt
EINECS	Contact for details

Quality Control

Our 2'-Deoxyinosine-5'-Triphosphate Trisodium Salt is manufactured under strict quality systems to ensure batch-to-batch consistency and reliability for sensitive applications. Each lot is subjected to rigorous analytical testing, including HPLC for purity and identity confirmation. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This material is hygroscopic (moisture-sensitive). For long-term stability, it is recommended to store desiccated. Allow the sealed container to reach room temperature before opening to minimize condensation and moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder or solid
Identification (HPLC/UV)	Conforms
Purity (HPLC)	≥ 95%
Assay (Enzymatic)	≥ 90%
Water Content (KF)	≤ 5.0%
pH (1% Solution)	6.5 - 8.5
Endotoxin	< 10 EU/mg
Filter Sterilization	0.2 µm filtered solution available

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.