Description

7-Azido-4-Methylcoumarin is a specialized heterocyclic organic compound belonging to the coumarin family, functionalized with an azido group. This unique structure makes it a valuable photoaffinity labeling agent and a versatile building block in chemical biology and materials science research. It is primarily sought after by researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors for developing novel probes, polymers, and active compounds.

Application

• Photoaffinity Labeling: Acts as a critical reagent for mapping biological binding sites and protein-ligand interactions due to its photoreactive azido group.
• Fluorescent Probe Synthesis: Serves as a precursor for developing sensitive fluorescent probes and sensors for bioimaging and diagnostic applications.
• Click Chemistry: Used as a key component in Cu(I)-catalyzed azide-alkyne cycloaddition (CuAAC) reactions for bioconjugation and polymer functionalization.
• Polymer & Materials Science: Incorporated into polymer backbones or surfaces to introduce photo-crosslinkable or clickable functionalities for advanced material design.
• Pharmaceutical Intermediate: Employed in the research and development of new drug candidates, particularly those targeting enzymes or receptors where covalent inhibition is desired.
• Agrochemical Research: Utilized in the synthesis of novel active ingredients or tracer molecules for studying mode of action and environmental fate.

Basic Information

Product Name	7-Azido-4-Methylcoumarin
CAS No.	95633-27-5
Molecular Formula	C₁₀H₇N₃O₂
Molecular Weight	201.18 g/mol
Synonyms	7-Azido-4-methyl-2H-chromen-2-one; 4-Methyl-7-azidocoumarin; 7-Azido-4-methylcoumarin; Azidomethylcoumarin; Photoaffinity Coumarin Derivative; Click Chemistry Coumarin; AMC Azide; Coumarin Azide
EINECS	Contact for details

Quality Control

Our 7-Azido-4-Methylcoumarin is manufactured under strict quality control protocols to ensure high purity and batch-to-batch consistency suitable for research and development. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry standards, and specifications can be tailored to meet specific project requirements upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C under an inert atmosphere (e.g., argon or nitrogen) to minimize oxidation and degradation. Keep away from heat, sparks, and open flame. For long-term storage, consider storing desiccated at -20°C.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95%
Melting Point	Contact for details
Water Content (KF)	< 0.5%
Residue on Ignition	< 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.