Description

Calcitonin, Human, Gly(8)- is a synthetic analogue of the human calcitonin hormone, specifically modified at the eighth amino acid position with glycine. This modification is engineered to enhance the peptide's stability and biological activity profile, making it a critical component for advanced pharmaceutical research and development. It is primarily utilized by biotechnology firms, academic research institutions, and pharmaceutical companies engaged in metabolic bone disease research, osteoporosis treatment development, and peptide-based therapeutic innovation.

Application

• Pharmaceutical Reference Standard: Serves as a high-purity calibrant for quality control and assay validation in drug manufacturing.
• Metabolic Bone Disease Research: Used in preclinical studies to investigate mechanisms of bone resorption and calcium regulation.
• Therapeutic Peptide Development: Acts as a key intermediate or active pharmaceutical ingredient (API) in the formulation of novel calcitonin-based therapies.
• Biochemical Assays: Employed in in vitro diagnostic test development and receptor binding studies.
• Academic & Clinical Research: Supports fundamental research into endocrinology, peptide chemistry, and hormone action.

Basic Information

Product Name	Calcitonin, Human, Gly(8)-
CAS No.	95548-37-1
Molecular Formula	C₁₄₅H₂₄₀N₄₄O₄₈S₂
Molecular Weight	3417.8 g/mol
Synonyms	Human Calcitonin Gly(8)-; Gly8-Calcitonin (human); [Gly8]-Calcitonin; hCT (Gly8); Calcitonin (human), 8-glycine; Salmon Calcitonin Analog; CALCA (8-Gly) peptide; Therapeutic Peptide 95548-37-1
EINECS	Contact for details

Quality Control

Our Calcitonin, Human, Gly(8)- is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, mass spectrometry for identity confirmation, and stringent tests for related substances and residual solvents. Certificates of Analysis (COA) detailing all specifications are provided to ensure compliance with your research and development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to prevent condensation and moisture uptake.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Single Impurity (HPLC)	≤ 1.0%
Water Content (KF)	≤ 5.0%
Peptide Content	≥ 80.0%
Biological Activity	Assay dependent; report available

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.