Description

1H-Indole-2-Carbonyl Chloride,5-Bromo is a high-purity, reactive chemical building block essential for advanced organic synthesis. This compound is a key intermediate for constructing complex heterocyclic molecules, offering a versatile handle for amide bond formation and further functionalization. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel indole-based drug candidates, including potential kinase inhibitors and receptor modulators.
• Agrochemical Research: Used to develop new generations of herbicides and plant growth regulators with specific biological activity.
• Material Science: Serves as a monomer or functionalizing agent for creating specialized polymers and advanced organic electronic materials.
• Chemical Biology: Employed in the design and synthesis of molecular probes and labeled compounds for biochemical and diagnostic applications.
• Academic & Contract Research: A valuable reagent for methodological development and exploratory synthesis in academic and industrial R&D laboratories.

Basic Information

Product Name	1H-Indole-2-Carbonyl Chloride,5-Bromo
CAS No.	95538-32-2
Molecular Formula	C9H5BrClNO
Molecular Weight	258.50 g/mol
Synonyms	5-Bromo-1H-indole-2-carbonyl chloride; 5-Bromoindole-2-carbonyl chloride; 5-Bromo-2-indolecarbonyl chloride; 5-Bromo-1H-indole-2-carboxylic acid chloride; 2-Carbonyl chloride-5-bromoindole; 95538-32-2; 5-Br-indole-2-COCl
EINECS	Contact for details

Quality Control

Our 1H-Indole-2-Carbonyl Chloride,5-Bromo is manufactured under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and FTIR, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with customer specifications and industry standards for fine chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic and moisture-sensitive nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition. Keep away from strong acids and incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.