Description

1H-Indole-2-Carbonylchloride,5-Methyl-(9Ci) CAS NO 95538-31-1 is a specialized indole derivative, specifically an acid chloride, that serves as a critical building block in advanced organic synthesis. This compound is valued for its high reactivity, enabling the efficient introduction of the 5-methylindole-2-carbonyl moiety into target molecules. It is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and complex intermediates.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of drug candidates targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Synthesis: Used in the development of novel pesticides and herbicides, leveraging the indole scaffold's bioactivity.
• Material Science Research: Building block for creating functional organic materials and dyes with specific photophysical properties.
• Peptide Mimetics: Employed in medicinal chemistry to create indole-based scaffolds that mimic peptide structures.
• Academic & R&D: Essential reagent in university and corporate research labs for exploring new chemical reactions and synthesizing complex heterocycles.
• Scale-up & Process Chemistry: Suitable for optimization in pilot plants and commercial manufacturing of high-value fine chemicals.

Basic Information

Product Name	1H-Indole-2-Carbonylchloride,5-Methyl-(9Ci)
CAS No.	95538-31-1
Molecular Formula	C10H8ClNO
Molecular Weight	193.63 g/mol
Synonyms	5-Methyl-1H-indole-2-carbonyl chloride; 5-Methylindole-2-carbonyl chloride; 1H-Indole-2-carbonyl chloride, 5-methyl-; 5-Methyl-1H-indole-2-carboxylic acid chloride; 95538-31-1; 5-Methylindole-2-carboxylic acid chloride; 2-Carbonylchloride-5-methyl-1H-indole
EINECS	Contact for details

Quality Control

Our 1H-Indole-2-Carbonylchloride,5-Methyl-(9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and FTIR, to ensure identity, purity, and consistency. Certificates of Analysis (COA) documenting all critical quality attributes are available upon request. We support development and commercial projects requiring material that meets stringent internal specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening. Recommended storage temperature is 2-8°C for long-term stability. Keep away from strong acids and incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.